Evidence map›Paper›PMID 41550202›Full record

ArticleOptics continuum2024

High-speed in vivo calcium recording using structured illumination with self-supervised denoising.

Forest Speed, Catherine A Saladrigas, Alec Teel, Sean Vieau, Victor M Bright, Juliet T Gopinath, Cristin G Welle, Diego Restrepo, Emily A Gibson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Optics continuum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Miniaturized widefield microscope for high speed in vivo voltage imaging.bioRxiv : the preprint server for biology · 2025
    Article
  4. Voltage Imaging with Periodic Structured Illumination.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Forest SpeedDepartment of Bioengineering, University of Colorado Anschutz, Aurora, CO 80045, USA.
Catherine A SaladrigasDepartment of Electrical, Energy and Computer Engineering, University of Colorado Boulder, Boulder, CO 80309, USA.
Alec TeelDepartment of Cell and Developmental Biology, University of Colorado Anschutz, Aurora, CO 80045, USA.
Sean VieauDepartment of Neurosurgery, University of Colorado Anschutz, Aurora, CO 80045, USA.
Victor M BrightDepartment of Mechanical Engineering, University of Colorado Boulder, Boulder, CO 80309, USA.
Juliet T GopinathDepartment of Electrical, Energy and Computer Engineering, University of Colorado Boulder, Boulder, CO 80309, USA.ORCID 0000-0003-2387-5371
Cristin G WelleDepartment of Neurosurgery, University of Colorado Anschutz, Aurora, CO 80045, USA.
Diego RestrepoDepartment of Cell and Developmental Biology, University of Colorado Anschutz, Aurora, CO 80045, USA.
Emily A GibsonDepartment of Bioengineering, University of Colorado Anschutz, Aurora, CO 80045, USA.

Funding

Development of 3D-FAST Optical Interface for Rapid Volumetric Neural Sensing and ModulationR01NS123665 · NINDS · UNIVERSITY OF COLORADO DENVER · PI GIBSON, EMILY, WELLE, CRISTIN G · 2021 to 2021
$2.7M
NINDS NIH HHS R01 NS123665
6 · The paper itself

Abstract

High-speed widefield fluorescence imaging of neural activity in vivo is fundamentally limited by fluctuations in recorded signal due to background contamination and stochastic noise. In this study, we show background and shot noise-reduced imaging of the ultrafast genetically encoded Ca

Identifiers

PMID41550202
PMCPMC12811017

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.