Evidence map›Paper›PMID 41550160›Full record

ArticlePharmaceutical science advances2024

Preparation and characterization of micellar nanoparticles using crude saponins from five Congolese plant species.

Pathy B Lokole, Nadège K Ngombe, Dave I Motomba, Justin B Safari, Michel K Mpuza, Rui W M Krause, Paulin K Mutwale, Christian I Nkanga

Abstract read
In one paragraph

Article in Pharmaceutical science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pathy B LokoleCentre de Recherche en Nanotechnologies Appliquées aux Produits Naturels (CReNAPN), Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kinshasa, B.P. 212, Kinshasa XI, Congo.
Nadège K NgombeCentre de Recherche en Nanotechnologies Appliquées aux Produits Naturels (CReNAPN), Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kinshasa, B.P. 212, Kinshasa XI, Congo.
Dave I MotombaCentre de Recherche en Nanotechnologies Appliquées aux Produits Naturels (CReNAPN), Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kinshasa, B.P. 212, Kinshasa XI, Congo.
Justin B SafariCentre for Chemico- and Bio-Medicinal Research (CCBR), Department of Chemistry, Faculty of Science, Rhodes University, PO Box 94, Grahamstown, 6140, Eastern Cape, South Africa.
Michel K MpuzaCentre d'Etudes des Substances Naturelles d'Origine Végétale (CESNOV), Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kinshasa, B.P. 212, Kinshasa XI, Congo.
Rui W M KrauseCentre for Chemico- and Bio-Medicinal Research (CCBR), Department of Chemistry, Faculty of Science, Rhodes University, PO Box 94, Grahamstown, 6140, Eastern Cape, South Africa.
Paulin K MutwaleCentre de Recherche en Nanotechnologies Appliquées aux Produits Naturels (CReNAPN), Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kinshasa, B.P. 212, Kinshasa XI, Congo.
Christian I NkangaCentre de Recherche en Nanotechnologies Appliquées aux Produits Naturels (CReNAPN), Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kinshasa, B.P. 212, Kinshasa XI, Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles (NPs) have significantly advanced medical applications, including drug delivery, immunotherapy, vaccines, and diagnostics. This versatility is partly due to the potential of tailoring NPs from multiple sources. Notably, saponins, amphiphilic plant metabolites, have shown great promise in NP formulation. This study explored the development of micellar NPs using saponin crude fractions (SCFs) extracted from five Congolese plant species:

Indexed as

Drug deliveryHemolysisMicellesNanoparticlesSaponinsSecondary metabolites

Identifiers

PMID41550160
PMCPMC12709945

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.