Evidence map›Paper›PMID 41550124›Full record

ArticleJournal of pediatrics. Clinical practice2026

Outcomes in Early Adulthood for Individuals Born Very Preterm and/or with Very Low Birth Weight: Evidence from Multinational Cohorts.

Hanifa Pilvar, Catia Nicodemo, Stavros Petrou, Brian A Darlow, Paula van Dommelen, Kari Anne I Evensen, Sarah Harris, John Horwood, Karen Mathewson, Saroj Saigal and 4 more

Abstract read
In one paragraph

Article in Journal of pediatrics. Clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hanifa PilvarNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Catia NicodemoNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Stavros PetrouNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Brian A DarlowUniversity of Otago, Otago, New Zealand.
Paula van DommelenThe Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands.
Kari Anne I EvensenNorwegian University of Science and Technology, Trondheim, Norway.
Sarah HarrisUniversity of Otago, Otago, New Zealand.
John HorwoodUniversity of Otago, Otago, New Zealand.
Karen MathewsonMcMaster University, Hamilton, Ontario, Canada.
Saroj SaigalMcMaster University, Hamilton, Ontario, Canada.
Louis SchmidtMcMaster University, Hamilton, Ontario, Canada.
Dieter WolkeUniversity of Warwick, Coventry, United Kingdom.
Lianne J WoodwardUniversity of Canterbury, Christchurch, New Zealand.
Sungwook KimNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Advances in neonatal care have improved survival rates for infants born very preterm (VP) and/or with very low birth weight (VLBW), yet their long-term outcomes into adulthood remain understudied. Objectives: To assess the impact of VP/VLBW status on mortality, educational attainment, and labor market outcomes in early adulthood using data from the RECAP Preterm Project. Methods: We used harmonized data from 5 nationally representative cohort studies in high-income countries (Canada, Germany, the Netherlands, New Zealand, and Norway) participating in the RECAP Preterm Project. Our sample included 2493 individuals born VP/VLBW and 496 control patients born at term. We used coarsened exact matching to compare adult outcomes between infants who were VP/VLBW and those born at term and an instrumental variable approach-using maternal nulliparity-to estimate the marginal effect of gestational age within the VP/VLBW group. Results: Mortality before adulthood was 16.7 percentage points greater among individuals who were VP/VLBW compared with control infants born at term (95% CI 13.2-20.2). Among survivors, the likelihood of attaining less than secondary education was 4.3 percentage points greater (95% CI -0.8 to 9.4). Differences in economic activity and working hours were small and uncertain. Within the VP/VLBW group, each additional week of gestational age was associated with a 6.8 percentage point reduction in mortality (95% CI -12.7 to -1.0), with weaker associations for educational and labor market outcomes. Conclusions: VP/VLBW birth is associated with elevated mortality and educational disadvantage in early adulthood. These findings highlight the importance of long-term support for this population beyond neonatal survival, particularly in education and development policy.

Indexed as

educational attainmentlong-run outcomespreterm birthRECAP project

Identifiers

PMID41550124
PMCPMC12810559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.