Evidence map›Paper›PMID 41550081›Full record

ArticlePlastic and reconstructive surgery. Global open2026

4D Lips Technique Based on Anatomy for Naturalization.

Melina Kichler, Marta Barros, Carolina de Freitas, Renata Viana, Marcelle Nogueira, Maria Bussade

Erratum issuedAbstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Erratum: 4D Lips Technique Based on Anatomy for Naturalization: Erratum.Plastic and reconstructive surgery. Global open · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Melina KichlerFrom the Independent Researcher, São Paulo, Brazil.
Marta BarrosFrom the Independent Researcher, São Paulo, Brazil.
Carolina de FreitasFrom the Independent Researcher, São Paulo, Brazil.
Renata VianaFrom the Independent Researcher, São Paulo, Brazil.
Marcelle NogueiraDermatology, University of São Paulo, São Paulo, Brazil.
Maria BussadeFrom the Independent Researcher, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lip augmentation has become a cornerstone of aesthetic procedures, particularly among younger patients seeking to enhance their natural lip features. A precise anatomical approach is essential to achieve balanced, natural-looking results while minimizing the risk of complications. This study introduced the 4D Lips technique, a multiphasic hyaluronic acid filler method designed to enhance lip shape while respecting anatomical landmarks. The technique is guided by 4 fundamental principles-dimension, distribution, dynamics, and desire-to ensure harmonious and individualized outcomes. Methods: Ten female patients underwent lip augmentation using a combination of subtechniques, including tubercle marking, vertical elongation, and vermilion border eversion. Two hyaluronic acid fillers with distinct viscoelastic properties were used: one with medium G' for structural support and another with low G' for contour refinement. Patient satisfaction and safety outcomes were systematically evaluated. Results: All patients reported satisfaction with the natural appearance of their enhanced lips. Mild and transient side effects, such as swelling, were observed and resolved spontaneously within a few days. No major complications were recorded. The structured, anatomy-based approach allowed for precise volumization, refined contouring, and preservation of natural lip dynamics. Conclusions: The 4D Lips technique underscores the value of an anatomy-informed and personalized approach to lip augmentation. By combining structural enhancement with a patient-centered perspective, this method achieves high satisfaction rates and a favorable safety profile. Nonetheless, the limitations of the study, including the small sample size, absence of a control group, and lack of long-term follow-up, warrant further investigation to validate these findings.

Identifiers

PMID41550081
PMCPMC12806590

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.