Evidence map›Paper›PMID 41549970›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Intraoperative color Doppler during manual vacuum aspiration prevents retained products of conception.

Tatsuya Yoshihara, Keito Nakayama, Dai Miyashita, Satoko Sasatsu, Maki Ogi, Yosuke Ono, Osamu Yoshino

Abstract read
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Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tatsuya YoshiharaDepartment of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan.ORCID https://orcid.org/0009-0001-2301-5075
Keito NakayamaDepartment of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan.
Dai MiyashitaDepartment of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan.
Satoko SasatsuDepartment of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan.
Maki OgiDepartment of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan.
Yosuke OnoDepartment of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan.
Osamu YoshinoDepartment of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether intraoperative confirmation of the disappearance of uterine cavity blood flow using color Doppler during manual vacuum aspiration (MVA) for missed miscarriage reduces the occurrence of retained products of conception (RPOC).

methodsWe conducted a retrospective cohort study of 202 patients who underwent MVA for missed miscarriage before 12 weeks of gestation at the University of Yamanashi between April 2019 and July 2025. Patients were divided into a flow-confirmation group, in which intraoperative transvaginal ultrasound with color Doppler was used to confirm the disappearance of blood flow, and a non-confirmation group. The primary outcome was the occurrence of RPOC diagnosed by postoperative ultrasound. Patient characteristics and surgical variables were compared between groups.

resultsRPOC occurred in 25 of 202 cases (12%). None of the 25 patients in the flow-confirmation group developed RPOC, whereas 14% of the 177 patients in the non-confirmation group did (P = 0.04). The surgeon's years of experience (2.6 ± 1.6 vs 4.9 ± 4.7 years, P = 0.004) and postoperative follow-up duration (1.9 ± 1.0 vs 3.3 ± 4.3 weeks, P = 0.02) were significantly shorter in the flow-confirmation group, but no other significant differences were found in baseline characteristics or surgical variables.

conclusionIntraoperative confirmation of the disappearance of uterine cavity blood flow using color Doppler during MVA is a simple, safe, and effective technique to prevent RPOC. This approach may reduce the need for repeat surgery and postoperative hemorrhage and could be incorporated into standard MVA protocols.

Indexed as

Abortion, MissedPlacenta, RetainedUltrasonography, Doppler, ColorUterusVacuum CurettageAdultFemaleHumansPregnancyRetrospective Studiesabortioncolor Doppler ultrasonographyretained products of conceptionultrasonographyvacuum curettage

Identifiers

PMID41549970
PMCPMC13278642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.