Evidence map›Paper›PMID 41549653›Full record

ArticleThe Journal of antimicrobial chemotherapy2026

Long-acting glycopeptides: what are the barriers to access in patients who need them most, and how can they be overcome?

Aleece MacPhail, Lucy O Attwood, Benjamin A Rogers

Abstract read
In one paragraph

Article in The Journal of antimicrobial chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Aleece MacPhailFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.ORCID 0000-0002-2332-8186
Lucy O AttwoodFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.ORCID 0000-0003-0447-7917
Benjamin A RogersFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.ORCID 0000-0001-6515-2118

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-acting glycopeptide antibiotics (LGPs), such as dalbavancin and oritavancin, are a novel class of antibiotic agents effective in the treatment of Gram-positive infections. The long half-life and relative ease of administration of LGPs make them a valuable treatment option for patients experiencing barriers to healthcare access. However, challenges for effective use remain, and disproportionately affect patients who would most benefit. These include high upfront costs, cost siloing, impractical and inconsistent medication approval processes and limited integration into existing multidisciplinary models of care. There is a clear need to improve funding arrangements, institutional workflows and models of care to promote safe and equitable access to LGPs, in line with processes developed for other high-cost medications.

Indexed as

Anti-Bacterial AgentsGlycopeptidesGram-Positive Bacterial InfectionsHealth Services AccessibilityHumansLipoglycopeptidesTeicoplaninVancomycinAnti-Bacterial AgentsdalbavancinGlycopeptidesLipoglycopeptidesoritavancinTeicoplaninVancomycin

Identifiers

PMID41549653
PMCPMC12813287

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.