Evidence map›Paper›PMID 41549624›Full record

ArticleMedical physics2026

Wide area surface dosimetry with conformal scintillator array for external beam radiotherapy.

Roman Vasyltsiv, Allison L Matous, Natasha Mulenga, Megan A Clark, Brian W Pogue, David J Gladstone, Lesley A Jarvis, Petr Bruza

Abstract read
In one paragraph

Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Roman VasyltsivThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
Allison L MatousDepartment of Radiation Oncology and Applied Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Natasha MulengaThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
Megan A ClarkThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
David J GladstoneThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
Lesley A JarvisDepartment of Radiation Oncology and Applied Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Petr BruzaThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
DoseRT™ : A Non-Contact Optical Patient and Beam Dosimetry System for Continuous in vivo Radiotherapy VerificationR44CA232879 · NCI · DOSEOPTICS, LLC · PI William Ware · 2018 to 2026
$5.2M
PHASE I FAST TRACK TOPIC 461 CONFORMABLE SCINTILLATOR ARRAY FOR IN VIVO DOSIMETRY DURING RT75N91024C00083 · NCI · DOSEOPTICS, LLC · PI BRUZA, PETR · 2024 to 2025
$2.4M
NCI NIH HHS 75N91024C00083NCI NIH HHS P30 CA023108NCI NIH HHS P30CA023108NCI NIH HHS R44 CA232879
6 · The paper itself

Abstract

backgroundIn vivo dosimetry is essential for treatment verification in modern radiotherapy, but existing techniques have significant limitations in their logistics of use related to time, accuracy of placement, temporal resolution, and non-uniform anatomy. Optical scintillation imaging dosimetry has shown potential to address several of these limitations, and the translation to conventional photon external beam radiotherapy was examined with a novel wide area imaging and sensing technique. PURPOSE: This study characterized a conformable scintillator array, for imaging real-time surface dose delivery over a wide curved surface area in conventional photon external beam radiotherapy. The variability was evaluated for dose, angular deviation, repetition rate, and field geometry while assessing its performance in field edge detection and measurement reproducibility using an anthropomorphic torso phantom.

methodsThe modular scintillator array consisting of 101 hexagonal scintillating elements was used together with a dual-camera stereovision system for 3D localization and a clinical Cherenkov imaging system for optical scintillation detection. The water equivalent thickness, dose linearity (10-800 MU), repetition rate stability (60-600 MU/min), and angular dependence of the scintillator array were characterized. Field edge detection was evaluated against radiochromic film through gamma analysis. System reproducibility was assessed through five consecutive deliveries simulating contralateral breast monitoring during whole breast treatment with a tangent beam.

resultsThe scintillator array demonstrated high dose linearity (R

conclusionThe conformable scintillator array imaging system provides spatially resolved, dynamic surface dosimetry with minimal workflow impact. Its ability to generate continuous dose maps across complex anatomical surfaces while maintaining angular correction capabilities addresses key limitations of current in vivo dosimetry approaches. This technology shows promise for clinical integration, particularly for treatments where wide area surface dosimetry is necessary.

Indexed as

RadiometryRadiotherapy, ConformalScintillation CountingHumansPhantoms, ImagingRadiotherapy DosageReproducibility of ResultsSurface Properties2D surface dosimetryphoton EBRTscintillation imaging

Identifiers

PMID41549624
PMCPMC13532102

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.