ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2026
Mechanistic Insights Into How Rewiring and Bifurcation Angle Affect DK-Crush Stent Deployment.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDouble kissing crush (DKC) is a preferred two-stent technique for complex coronary bifurcation lesions. Proximal cell rewiring is routinely recommended to reduce technical failure, and DKC is considered effective across various bifurcation angles. However, it remains unclear whether this standard approach is optimal for all patients.
aimsThis study investigates the interaction between bifurcation angle and rewiring configuration to identify anatomy-specific strategies.
methodsComputational modeling of the DKC procedure was used to simulate 12 DKC procedures across three left main bifurcation angles (45°, 70°, and 100°) and four rewiring configurations: proximal-proximal (P-P), proximal-distal (P-D), distal-proximal (D-P), and distal-distal (D-D). Evaluation metrics included stent malapposition, side branch ostium clearance, arterial wall stress, low time-averaged endothelial shear stress, and high shear rates.
resultsDKC performed in wide bifurcations (100°) resulted in worse outcomes, with malapposition reaching 18%, side branch clearance down to 23%, and up to twice the exposure to adverse high shear rates compared to narrower angles. In contrast, intermediate (70°) and narrow (45°) angles generally resulted in more favorable outcomes, though optimal rewiring varied by angle. Proximal strategies, that is, P-P and P-D, were most effective at 70°, while D-D performed best at 45°. No single strategy was consistently superior across all bifurcation angles.
conclusionsDKC outcomes depend on bifurcation angle and can be optimized by tailoring rewiring strategies, challenging the current clinical understanding. These findings support anatomy-specific procedural planning and intravascular imaging to guide rewiring. This study provides a mechanistic rationale to improve clinical decision-making and tailor bifurcation interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.