Evidence map›Paper›PMID 41549298›Full record

ArticleBMC research notes2026

Correlation between Humphrey Field Analyser perimetric outcomes and macular thickness in diabetic retinopathy patients, diabetic individuals without retinopathy, and control subjects in Trinidad and Tobago.

Kingsley Ekemiri, Chidum Ezenwaka, Reyanna Ramkissoon, Anil Ramsaran, Chioma Ekemiri, Esther Daniel, Kathy-Ann Lootawan, Linda Ekwe

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Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Kingsley EkemiriSchool of Optometry, Faculty of Health and Medical Sciences, Abia State University, Uturu, Nigeria. iamekemiri@gmail.com.ORCID http://orcid.org/0000-0003-3881-7502
Chidum EzenwakaDepartment of Para-Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St Augustine Campus, St Augustine, Trinidad and Tobago.
Reyanna RamkissoonOptometry Unit, Department of Clinical Surgical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Anil RamsaranOptometry Unit, Department of Clinical Surgical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Chioma EkemiriDepartment of Health Promotion, The University of the West Indies, St. Augustine Campus, St Augustine, Trinidad and Tobago.
Esther DanielSchool of Nursing, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, St Augustine, Trinidad and Tobago.
Kathy-Ann LootawanSchool of Nursing, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, St Augustine, Trinidad and Tobago.
Linda EkweOptometry Department, Federal Medical Center, Makurdi, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study examined the relationship between visual field performance measured with the Humphrey Field Analyzer and macular thickness measured using optical coherence tomography across three groups: individuals without diabetes, individuals with diabetes but no diabetic retinopathy, and individuals with diabetic retinopathy. The aim was to determine whether structural and functional measures show meaningful associations within and across disease stages in a Trinidad and Tobago population.

resultsIn unadjusted comparisons, macular and visual-field measures differed across groups (all p < 0.001). After age adjustment, most between-group differences were no longer significant, and age independently predicted VFI, confirming age as a major confounder. Within-group, age-adjusted associations persisted in DR (OD): lower VFI correlated with greater superior (partial r = − 0.519, p = 0.027) and temporal ETDRS thickness (partial r = − 0.585, p = 0.011), and higher PSD correlated with greater superior (partial r = + 0.603, p = 0.013) and temporal thickness (partial r = + 0.592, p = 0.016); all four remained significant after FDR correction. Macular total volume showed limited functional relevance. In DM_no_DR (exploratory), small-sample regressions suggested similar direction, but estimates were imprecise. MD was not analyzed via ANCOVA due to incomplete data.

Indexed as

Diabetic RetinopathyMacula LuteaVisual FieldsVisual Field TestsAdultAgedFemaleHumansMaleMiddle AgedTomography, Optical CoherenceTrinidad and TobagoDiabeticsMaculaOptical coherence tomographyRetinopathyVisual field assessment

Identifiers

PMID41549298
PMCPMC12895719

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