Evidence map›Paper›PMID 41549205›Full record

ReviewJournal of fluorescence2026

Dimerization-Enhanced Excimer Probe for Wash-Free Plasma Membrane Fluorescence Imaging.

Bailin Guo, Enju Wang, Yanling Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Large Stokes shift fluorophores fromChemical science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bailin GuoKey Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry & Chemical Engineering, Hainan Normal University, Haikou, 571158, P. R. China.
Enju WangKey Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry & Chemical Engineering, Hainan Normal University, Haikou, 571158, P. R. China. enjuwang@163.com.
Yanling LiuKey Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry & Chemical Engineering, Hainan Normal University, Haikou, 571158, P. R. China.

Funding

Hainan Provincial Natural Science Foundation of China 222MS059
6 · The paper itself

Abstract

Compared to monomeric counterparts, excimer probes exhibit significantly red-shifted spectra, broadened emission profiles, and enhanced Stokes shifts, exhibiting distinctive advantages in bioimaging applications. In this work, we developed an excimer-forming membrane-targeting fluorogenic probe (DIPP) through covalent conjugation between two triphenylimidazole moieties via a 1,5-bis(pyridin-1-yl)pentane linker. In various organic solvents, DIPP demonstrated exclusive excimer fluorescence, except in DMSO where monomer-excimer dual emission was observed, whereas its monomeric counterpart (MIPP) exhibits predominant monomer fluorescence, demonstrating that dimerization enhances excimer formation. Notably, DIPP displays negligible fluorescence in aqueous solution but exhibits significantly enhanced excimer emission intensity upon incorporation into SDS micelles. Leveraging the environmental sensitivity of excimer emission, DIPP was employed as a membrane-targeting fluorescent probe demonstrating multiple advantages: bright red emission (> 610 nm), a large Stokes shift (Δλ > 210 nm), low cytotoxicity, rapid cellular internalization (~ 5 min), and wash-free imaging capability.

Indexed as

Cell MembraneFluorescent DyesOptical ImagingDimerizationHeLa CellsHumansImidazolesFluorescent DyesImidazolesAmphiphilicityCell membraneExcimer emissionTriphenylimidazole dimerWash-free imaging

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.