Evidence map›Paper›PMID 41548974›Full record

ArticleAnnals of hepato-biliary-pancreatic surgery2026

Left extended hepatectomy (H123458-B) versus right extended hepatectomy (H145678-B) for hilar cholangiocarcinoma: A single center comparative analysis of surgical outcomes and survival.

Fahim Kanani, Esther Ovdat, Muhammed Younis, Guy Meyerovich, Nir Messer, Yaacov Goykhman, Nir Lubezky

Abstract read
In one paragraph

Article in Annals of hepato-biliary-pancreatic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fahim KananiDepartment of HPB and Transplant Surgery, Division of Surgery, Tel Aviv Sourasky Medical Center, Gray University of Medicine and Science, Tel Aviv, Israel.ORCID https://orcid.org/0009-0001-9754-5028
Esther OvdatDepartment of HPB and Transplant Surgery, Division of Surgery, Tel Aviv Sourasky Medical Center, Gray University of Medicine and Science, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-2110-8235
Muhammed YounisDepartment of HPB and Transplant Surgery, Division of Surgery, Tel Aviv Sourasky Medical Center, Gray University of Medicine and Science, Tel Aviv, Israel.ORCID https://orcid.org/0000-0001-5956-0916
Guy MeyerovichDepartment of HPB and Transplant Surgery, Division of Surgery, Tel Aviv Sourasky Medical Center, Gray University of Medicine and Science, Tel Aviv, Israel.ORCID https://orcid.org/0000-0003-0537-6317
Nir MesserDepartment of HPB and Transplant Surgery, Division of Surgery, Tel Aviv Sourasky Medical Center, Gray University of Medicine and Science, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-4686-9583
Yaacov GoykhmanDepartment of HPB and Transplant Surgery, Division of Surgery, Tel Aviv Sourasky Medical Center, Gray University of Medicine and Science, Tel Aviv, Israel.ORCID https://orcid.org/0009-0002-9627-1755
Nir LubezkyDepartment of HPB and Transplant Surgery, Division of Surgery, Tel Aviv Sourasky Medical Center, Gray University of Medicine and Science, Tel Aviv, Israel.ORCID https://orcid.org/0000-0001-9355-4405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds/Aims: Surgical resection is the only curative treatment for cholangiocarcinoma. In selected cases, extended hepatectomies, including right extended hepatectomy (REH; H145678-B) and left extended hepatectomy (LEH; H123458-B), are required. This study compares perioperative outcomes and long-term survival between LEH and REH. Methods: We retrospectively reviewed prospectively maintained data for all patients who underwent extended hepatectomies for hilar cholangiocarcinoma at a single institution between 2016 and 2022. Perioperative metrics and long-term outcomes were compared between groups. Results: Ten patients underwent LEH and 12 underwent REH. Future liver remnant was significantly greater in the LEH group (41% vs. 30%), and fewer LEH patients required volume manipulation (20% vs. 58%). Rates of major vascular resection were similar (LEH: 50% vs. REH: 58%). No patients in the LEH group developed post-hepatectomy liver failure (PHLF), compared to 41% in the REH group ( Conclusions: LEH may offer a superior safety profile, with lower PHLF incidence and shorter hospital stays compared to REH, while achieving similar oncologic outcomes. In anatomically suitable cases, LEH should be considered a potentially safer option for hilar cholangiocarcinoma.

Indexed as

Extended hepatectomyH123458-BH145678-BKlatskin tumor

Identifiers

PMID41548974
PMCPMC12958845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.