Evidence map›Paper›PMID 41548607›Full record

Trial reportJournal of substance use and addiction treatment2026

Real-time peer-navigation support during community re-entry for adults with opioid use disorder.

Adati Tarfa, Melissa Borker, Margaret Lancaster, Reuben Santiago, Angela Di Paola, Cynthia Frank, Sandra A Springer

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Journal of substance use and addiction treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adati TarfaDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA; Center for Interdisciplinary Research on AIDS, Yale University School of Public Health, New Haven, CT, USA.
Melissa BorkerColumbia University Mailman School of Public Health, NY, New York, USA.
Margaret LancasterLedge Light Health District, New London, CT, USA.
Reuben SantiagoLedge Light Health District, New London, CT, USA.
Angela Di PaolaDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA; Center for Interdisciplinary Research on AIDS, Yale University School of Public Health, New Haven, CT, USA.
Cynthia FrankDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.
Sandra A SpringerDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA; Center for Interdisciplinary Research on AIDS, Yale University School of Public Health, New Haven, CT, USA; Veterans Administration Connecticut Healthcare System, Department of Internal Medicine, Division of Infectious Diseases, Newington VA Medical Center, Newington, CT, USA. Electronic address: Sandra.springer@yale.edu.

Funding

Long-acting buprenorphine vs. naltrexone opioid treatments in CJS-involved adultsU01DA047982 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FARABEE, DAVID J, GRYCZYNSKI, JAN · 2019 to 2024
$20.3M
Ending HIV: Bringing Integrated Prevention and Treatment Services to People Who Use Drugs Where They LiveDP1DA056106 · NIDA · YALE UNIVERSITY · PI SANDRA Ann SPRINGER · 2022 to 2026
$6.0M
NIDA NIH HHS DP1 DA056106NIDA NIH HHS U01 DA047982
6 · The paper itself

Abstract

backgroundFor individuals with opioid use disorder (OUD) re-entering the community after incarceration, peer navigator (PN) support is increasingly implemented to support treatment initiation and continuity. However, little is known about the specific services PNs deliver in real-time encounters, contexts in which these services occur, and how they address barriers that affect access to medications for OUD (MOUD). This study presents the first empirically derived typology of PN support for criminal legal-involved (CLI) adults with OUD.

methodsWe applied qualitative content analysis (QCA) to PN encounters from the Connecticut (CT) site of a multi-site randomized controlled trial (RCT) evaluating extended-release buprenorphine (XR-B), extended-release naltrexone (XR-NTX), and enhanced treatment as usual (ETAU) among CLI adults with OUD. Of the 151 individuals enrolled in CT, this analysis focuses on the 108 participants who had at least one PN encounter. Two PNs with lived experience supported participants across all study arms and recorded 1316 real-time engagement notes in REDCap between January 2021 and January 2024. Descriptive quantitative data were triangulated with QCA findings, and Lincoln and Guba's criteria guided qualitative analytic rigor.

resultsParticipants averaged 37.6 years (SD ± 7.7); 72% were men, 85% White, and 23% Hispanic. Three domains of support were identified: (1) Direct Services (41.9% of encounters), where PNs provided tangible resources, including transportation (29.3% of direct services) to pharmacies, court dates, and the provision of food and clothing. (2) Informational Services (40.6% of all encounters) involved educating peers about resources (29.1% of informational services), including employment for CLI individuals, as well as goal setting (12.0% of informational services) and MOUD visit reminders. (3) Facilitation Services (17.5% of all encounters) involved PNs helping participants navigate systems through advocacy (32.8% of facilitation services) with parole officers or housing managers, negotiating during evictions, and assistance with paperwork to receive social service benefits (14.5% of facilitation services). These service patterns reflected participants' high needs: 41.1% had unstable housing, only 4.4% were employed full-time, and 13.5% reported active substance use during PN encounters.

conclusionsPeer Navigators provide direct, informational, and facilitation support during community re-entry that can help with MOUD access. Future research should examine how these service domains align with participant priorities and contribute to treatment outcomes.

Indexed as

Opioid-Related DisordersPatient NavigationPeer GroupAdultBuprenorphineConnecticutDelayed-Action PreparationsFemaleHumansMaleNaltrexoneNarcotic AntagonistsOpiate Substitution TreatmentBuprenorphineDelayed-Action PreparationsNaltrexoneNarcotic Antagonists

Identifiers

PMID41548607
PMCPMC12895323

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.