Evidence map›Paper›PMID 41548146›Full record

ArticleMicrocirculation (New York, N.Y. : 1994)2026

Hyperspectral Imaging Reveals High Water and Hemoglobin Content at Rest and Decreased Oxygen Levels After Physical Activity at the Residual Limb of Non-Dysvascular Lower Limb Amputees.

Luis A Pardo, Charlotte Brinkmeyer, Meike A Wilke, Lisa Lorbeer, Marc Varel, Arndt F Schilling, Jennifer Ernst

Abstract read
In one paragraph

Article in Microcirculation (New York, N.Y. : 1994), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luis A PardoHannover Medical School, Department of Trauma Surgery, Hannover, Germany.
Charlotte BrinkmeyerDepartment of Trauma Surgery, Orthopedic Surgery and Plastic Surgery, University Medical Center Göttingen, Göttingen, Germany.
Meike A WilkeFaculty of Life Sciences, Hamburg University of Applied Sciences (HAW), Hamburg, Germany.
Lisa LorbeerHannover Medical School, Department of Trauma Surgery, Hannover, Germany.
Marc VarelDepartment of Trauma Surgery, Orthopedic Surgery and Plastic Surgery, University Medical Center Göttingen, Göttingen, Germany.
Arndt F SchillingDepartment of Trauma Surgery, Orthopedic Surgery and Plastic Surgery, University Medical Center Göttingen, Göttingen, Germany.
Jennifer ErnstHannover Medical School, Department of Trauma Surgery, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSkin integrity is one factor determining residual limb health. Oxygen deficiency caused by energy consumption and/or mechanical stress is the most common reason for skin breakdown at the residual limb (RL), limiting physical activity and causing residual limb pain (RLP). This study aims to detect differences in microcirculation at rest (T1) and after walking for 6 min (T2) with a socket prosthesis at different zones at the residual limb (RL) and the corresponding areas at the sound limb (SL).

methodsAmputation and RLs' demographics as limb circumference (LCF), subcutaneous fat thickness (SCFT) and microcirculatory parameters as tissue oxygenation saturation (StO

resultsLCF and SCFT were lower at the RL than at the SL. A significant reduction of NIRPI after walking was observed at location F2, affecting both limbs. StO DISCUSSION: These findings demonstrate localized exercise-related reductions in oxygenation at the distal RL, whereas microcirculation of the SL remained unchanged. Underlying factors and a possible impact on the overall residual limb health need further investigation.

Indexed as

AmputeesExerciseHemoglobinsHyperspectral ImagingLower ExtremityOxygenWaterFemaleHumansMaleMicrocirculationRestHemoglobinsOxygenWateredemahyperspectral imagingmajor limb amputationmicrocirculationresidual limb healthskinulcersvenous stasis

Identifiers

PMID41548146
PMCPMC12812306

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.