ArticleNature communications2026
A single valine to leucine switch disrupts Plasmodium falciparum AP2-G DNA binding and reveals GDV1's role in ap2-g activation.
Surendra K Prajapati, Jeffrey X Dong, Belinda J Morahan, Thoai Dotrang, Michelle C Barbeau, April E Williams, Daniel Hupalo, Matthew D Wilkerson, Clifton L Dalgard, Bjorn F C Kafsack and 2 more
Abstract read
In one paragraphArticle in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
12 authors.
Surendra K PrajapatiDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. surendra.prajapati.ctr@usuhs.edu.ORCID http://orcid.org/0000-0003-1188-668X Jeffrey X DongDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Belinda J MorahanLaboratory of Malaria and Vector Research, NIAID, NIH, Rockville, MD, USA.
Thoai DotrangDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Michelle C BarbeauDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
April E WilliamsDepartment of Molecular Biology, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
Daniel HupaloDepartment of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Matthew D WilkersonDepartment of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Funding
Spatial Patterning During DevelopmentP50GM071508 · NIGMS · PRINCETON UNIVERSITY · PI GAMMIE, ALISON E · 2004 to 2013
$30.6MNIGMS NIH HHS P50 GM071508United States Department of Defense | Uniformed Services University of the Health Sciences (Uniformed Services University) C073384316U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01 AI069314 and R01 AI103638U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01 AI076276, R01-AI125565 P50
6 · The paper itselfAbstract
Sexual commitment in Plasmodium parasites is essential for malaria transmission, yet the signaling events initiating sexual conversion in only a subpopulation of parasites remain unclear. We discovered a single valine(V
Indexed as
DNA, ProtozoanLeucinePlasmodium falciparumProtozoan ProteinsTranscription FactorsValineAnimalsMutationProtein BindingDNA, ProtozoanLeucineProtozoan ProteinsTranscription FactorsValine
Identifiers
PMID41547993
PMCPMC12913604
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390