Evidence map›Paper›PMID 41547773›Full record

Trial reportBMC surgery2026

Clinical efficacy of gasless trans-subclavian approach and trans-axillary approach endoscopic thyroidectomy for papillary thyroid carcinoma: a prospective randomized study.

Mengsha Zou, Jianan Zhang, Jiawei Tang, Shang Shi, Chen Shen, Gaoxiang Chen

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mengsha ZouThe Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315040, P. R. China.
Jianan ZhangThe Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315040, P. R. China.
Jiawei TangThe Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315040, P. R. China.
Shang ShiThe Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315040, P. R. China.
Chen ShenThe Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315040, P. R. China.
Gaoxiang ChenThe Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315040, P. R. China. lhlchengaoxiang@nbu.edu.cn.

Funding

Ningbo Public Welfare Science and Technology Project 2022S051
6 · The paper itself

Abstract

backgroundEndoscopic technology continues to evolve, expanding the clinical application spectrum of various endoscopic thyroidectomy approaches. However, comparative studies between gasless trans-subclavian approach endoscopic thyroidectomy (GTSA-ET) and gasless trans-axillary approach endoscopic thyroidectomy (GTAA-ET) remain notably scarce in the current literature. In this study, we aimed to compare the clinical efficacy of GTSA-ET and GTAA-ET in the treatment of papillary thyroid carcinoma (PTC).

methodsThis study was conducted on 160 patients with cN0-stage PTC who were enrolled between December 2023 and July 2024. The patients were randomly assigned to either the GTSA-ET group (n = 80) or the GTAA-ET group (n = 80) at a 1:1 ratio. Perioperative outcomes, postoperative complications, postoperative neck function, surgical site pain and numbness scores, and incision satisfaction were systematically observed and compared between the two groups.

resultsCompared with the GTAA-ET group, the GTSA-ET group exhibited a significantly shorter operative time (p < 0.001), a higher rate of complete central compartment (level VI/VII where applicable) exposure (p = 0.028), and a greater total number of dissected central lymph nodes (p < 0.001). At 1 month postoperatively, patients in the GTSA-ET group reported significantly less neck movement traction sensation than those in the GTAA-ET group (p < 0.05). No statistically significant difference was observed in swallowing traction sensation between the two groups (p > 0.05). Additionally, patients in the GTSA-ET group experienced significantly milder pain and numbness in the anterolateral chest region compared with the GTAA-ET group (p < 0.05). There was no significant difference in incision satisfaction scores between the two groups (p > 0.05).

conclusionsGTSA-ET offers distinct advantages over GTAA-ET, including a shorter operative time, a higher rate of complete central compartment (level VI/VII where applicable) exposure (supporting more thorough central compartment lymph node dissection), a greater number of dissected central lymph nodes, temporarily reduced postoperative neck traction sensation, and less anterolateral chest pain/numbness. Thus, GTSA-ET represents a safe, effective, and aesthetically preserving surgical option for patients with PTC.

trial registrationChinese Clinical Trial Registry number, ChiCTR2400086466. Retrospectively registered on 02/07/2024.

Indexed as

EndoscopyThyroid Cancer, PapillaryThyroidectomyThyroid NeoplasmsAdultAxillaFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsProspective StudiesTreatment OutcomeEndoscopic thyroidectomyGaslessPapillary thyroid carcinomaTrans-axillary approachTrans-subclavian approach

Identifiers

PMID41547773
PMCPMC12896082

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.