20% Caloric Restriction did not Impact Bone Health nor Exercise-Induced Elevations in Bone Mass in Young Female Rats.

Ken D Sumida, Brady Slater, Haley Folta, Kassandra Lee, Sarina Karwande, Quinton Wong, S Victoria Jaque, Frank Frisch

Abstract read

In one paragraph

Article in Calcified tissue international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ken D SumidaDepartments of Health Sciences, Chapman University, One University Drive, Orange, CA, 92866, USA. sumida@chapman.edu.ORCID http://orcid.org/0000-0001-5025-2618

Brady SlaterDepartments of Health Sciences, Chapman University, One University Drive, Orange, CA, 92866, USA.

Haley FoltaDepartments of Health Sciences, Chapman University, One University Drive, Orange, CA, 92866, USA.

Kassandra LeeDepartments of Health Sciences, Chapman University, One University Drive, Orange, CA, 92866, USA.

Sarina KarwandeDepartments of Health Sciences, Chapman University, One University Drive, Orange, CA, 92866, USA.

Quinton WongDepartments of Health Sciences, Chapman University, One University Drive, Orange, CA, 92866, USA.

S Victoria JaqueDepartment of Kinesiology, California State University, Northridge, CA, USA.

Frank FrischDepartments of Health Sciences, Chapman University, One University Drive, Orange, CA, 92866, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to determine if a 6-week 20% caloric restrictive (CR) diet, with or without resistance training, would impact bone health in growing young female rats. Forty female rats (~ 5 wks old) were randomly divided into the following groups: baseline (n = 8), sedentary fed a normal diet (N, n = 8), sedentary fed a 20% CR diet (D, n = 8), resistance trained fed a normal diet (NT, n = 8), and resistance trained fed a 20% CR diet (DT, n = 8). The exercise groups were conditioned to climb a vertical ladder 4 consecutive times (per exercise session) with weights appended to their tail 3 days/wk for a total of 6 wks. Tibial bone mineral density (BMD) was assessed via dual-energy x-ray absorptiometry scans. After 6 wks, the body mass (mean ± SD) for CR fed groups (D = 232.6 ± 26.3 g & DT = 216.6 ± 17.9 g) were significantly lower than the normal fed groups (N = 266.1 ± 31.5 g & NT = 251.9 ± 23.4 g). Tibial BMD (in g/cm

Indexed as

Bone and BonesBone DensityCaloric RestrictionPhysical Conditioning, AnimalAbsorptiometry, PhotonAnimalsFemaleRatsRats, Sprague-DawleyResistance TrainingTibiaBMDBone mechanical propertiesCaloric restrictionDXATibia

Identifiers

PMID41547668

DOI10.1007/s00223-025-01469-4

PMCPMC12812087

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.