Evidence map›Paper›PMID 41546824›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2026

Simplifying the esophagogastric junction contractile integral calculation.

Arianna Vittori, Andrés R Latorre-Rodríguez, Sumeet K Mittal

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reconsidering simplified metrics of esophagogastric junction barrier function.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arianna VittoriNorton Thoracic Institute, St. Joseph's Hospital and Medical Center, 500 W Thomas Road, Suite 500, Phoenix, AZ, 85013, USA.ORCID http://orcid.org/0000-0001-8681-968X
Andrés R Latorre-RodríguezNorton Thoracic Institute, St. Joseph's Hospital and Medical Center, 500 W Thomas Road, Suite 500, Phoenix, AZ, 85013, USA.ORCID http://orcid.org/0000-0003-3401-8623
Sumeet K MittalNorton Thoracic Institute, St. Joseph's Hospital and Medical Center, 500 W Thomas Road, Suite 500, Phoenix, AZ, 85013, USA. sumeet.mittal@commonspirit.org.ORCID http://orcid.org/0000-0003-2760-3891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe esophagogastric junction contractile integral (EGJ-CI) is a manometric parameter used to assess EGJ function. EGJ-CI must be manually calculated using a multi-step process. An earlier metric, the lower esophageal sphincter pressure integral (LESPI), is conceptually similar to EGJ-CI, but has a more straightforward calculation algorithm.

aimsThis study aimed at proposing a new, easier to calculate metric, the modified EGJ-CI (m-EGJ-CI) and to compare its fidelity to EGJ-CI.

methodsAfter Institutional Review Board (IRB) approval, we conducted a cross-sectional study. High-resolution manometry studies performed between February 2018 and October 2024 at our center were retrieved. Patients with prior foregut procedures, distal esophageal spasm, hypercontractile esophagus, EGJ outflow disorders, hiatal hernias > 5 cm and lung transplant candidates/recipients were excluded. An experienced interpreter calculated the EGJ-CI and m-EGJ-CI for each study. Correlations were assessed using Spearman's rank coefficient. The complexity of each parameter was estimated based on the calculation time required.

resultsStudies from 84 patients (58 women [69%]; median age, 61 years [IQR 49.5-69.5]) were re-analyzed. A strong positive correlation between EGJ-CI and m-EGJ-CI was found (ρ = 0.839 [95%CI = 0.72-0.96], p < 0.05). The cumulative time for m-EGJ-CI calculations was significantly lower than that for EGJ-CI (15.7 vs. 60.3 min, p < 0.05).

conclusionsThe EGJ-CI calculation as an indicator of EGJ competence may be overly complex and time-consuming. The m-EGJ-CI saves time without compromising fidelity to EGJ-CI and can potentially be automated in future software versions.

Indexed as

Esophagogastric junctionGastroesophageal reflux diseaseLower esophageal sphincter

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.