Evidence map›Paper›PMID 41546778›Full record

ArticleCancer causes & control : CCC2026

Beyond the check-up: how well-child exams, pediatric specialists, and provider recommendations can close HPV vaccine gaps for Chinese American Teens.

Lin Zhu, Xinrui Li, Elaine Zhiqing Liu, Philip T Siu, Shumenghui Zhai, Chun Pan, Nikki Cao, Grace X Ma

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lin ZhuCenter for Asian Health, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA. lin.zhu@temple.edu.
Xinrui LiPsychology and Human Development Department, Peabody College, Vanderbilt University, Nashville, TN, USA.
Elaine Zhiqing LiuDepartment of Urban Health and Population Science, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Philip T SiuEsperanza Health Center, Philadelphia, PA, USA.
Shumenghui ZhaiSchool of Nursing, Pacific Lutheran University, Tacoma, WA, USA.
Chun PanDepartment of Mathematics and Statistics, Hunter College, New York, NY, USA.
Nikki CaoCenter for Asian Health, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Grace X MaCenter for Asian Health, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.

Funding

TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221705 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI GRACE X. MA · 2018 to 2026
$16.3M
Examining the Integrative Effects of Adolescent, Parent, Provider, and Practice Level Factors on Adolescents' HPV Vaccine Uptake across Six Asian American SubgroupsR03CA259633 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI ZHU, LIN · 2022 to 2023
$166k
NCI NIH HHS R03 CA259633NCI NIH HHS R03CA259633NCI NIH HHS U54 CA221705
6 · The paper itself

Abstract

purposeThis study aimed to identify provider- and practice-level factors influencing human papillomavirus (HPV) vaccine uptake among Chinese American (CA) adolescents. Despite increasing public health efforts, HPV vaccination rates in this population remain suboptimal, and knowledge on the link between provider/practice characteristics and vaccine uptake is limited.

methodsWe analyzed data from 1,272 CA adolescents (aged 13-17) using the National Immunization Survey-Teen (2015-2019) datasets. Key measures included HPV vaccine initiation and completion (based on proxy reporting and verification), accompanied by various multilevel factors: provider-level (recommendation, specialty), practice-level (facility type, vaccine acquisition, well-child exam), parent-level (mother's education, marital status), and adolescent-level characteristics. Weighted descriptive statistics and stepwise multivariate logistic regression were used to examine associations.

resultsOverall, 71.22% of CA adolescents initiated at least one HPV vaccine dose, while 48.14% completed the regimen. Provider's recommendation (initiation OR = 21.50, completion OR = 8.12), having a pediatrician (initiation OR = 5.37, completion OR = 3.20), and receiving the 11-12-year-old well-child exams significantly predict both initiation and completion. Regional disparities were observed, with adolescents in the Northeast and West showing higher completion rates than those in the South. Unexpectedly, adolescents not enrolled in school and those with mothers who had less than 12 years of education or were unmarried showed higher completion rates.

conclusionProvider recommendations and pediatric care are crucial for improving HPV vaccination rates among CA adolescents. Addressing regional disparities and implementing targeted interventions, including enhanced provider training focused on culturally sensitive communication, are essential to dismantle systemic barriers and improve comprehensive vaccination coverage in this underserved population.

Indexed as

AsianPapillomavirus InfectionsPapillomavirus VaccinesAdolescentChinaFemaleHealth Knowledge, Attitudes, PracticeHumansMaleUnited StatesVaccinationPapillomavirus VaccinesAdolescentsChinese AmericanDisaggregated dataHuman papillomavirus vaccineMultilevel factors

Identifiers

PMID41546778
PMCPMC12812084

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.