Evidence map›Paper›PMID 41546715›Full record

ArticleClinical oral investigations2026

Osseous free flap vs. Bridging plate mandibular reconstruction: a retrospective cohort study on perioperative complications of 335 patients.

Philipp Lampert, Jakob Fenske, Kilian Kreutzer, Henri Kreiker, Norbert Neckel, Steffen Koerdt, Max Heiland, Carsten Rendenbach

Abstract readComparative Study
In one paragraph

Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philipp LampertCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. philipp.lampert@charite.de.
Jakob FenskeCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Kilian KreutzerCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Henri KreikerCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Norbert NeckelCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Steffen KoerdtCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Max HeilandCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Carsten RendenbachCorporate Member of Freie, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study compared postoperative complication rates between bridging plate reconstruction with soft tissue free flaps and osseous free flaps for segmental mandibular defects. MATERIALS AND

methodsThis retrospective study compared postoperative outcomes between both techniques in 335 reconstructions of segmental mandibular defects operated over 8 years. The N-1 χ2-test, Fisher’s exact test and Mann-Whitney-U test were used to test for statistical significance after mode and mean imputation were performed on independent variables with missing data.

resultsPatients who received bridging plate reconstructions were significantly older (74.4 ± 10.5 vs. 63.4 ± 10.6 years, p < 0.001) and had higher rates of hypertension (67.6% vs. 40.6%, p = 0.002), atherosclerosis (27.0% vs. 12.8%, p = 0.020), and prophylactic anticoagulation (21.6% vs. 8.7%, p = 0.014). Treatment indications differed significantly, with malignant tumors in 59.5% vs. 78.5% and osteonecrosis in 40.5% vs. 21.5% of bridging plate and osseous reconstructions, respectively (p < 0.001). Mortality (24.3% vs. 10.1%, p = 0.011) and pneumonia rates (13.5% vs. 4.7%, p = 0.029) were higher in the bridging plate group. Plate exposure (21.6% vs. 24.8%, p = 0.669), fixation failure (5.4% vs. 6.0%, p = 0.878), and early flap loss (5.4% vs. 4.4%, p = 0.773) showed no significant differences. Bridging plate reconstructions had shorter surgery times (8.4 ± 2.0 vs. 9.6 ± 2.2 h, p = 0.002) and fewer wound infections (13.5% vs. 30.9%, p = 0.028).

conclusionsOur findings emphasize the value of bridging plate reconstruction as a pragmatic and effective option when osseous reconstruction is contraindicated and advocate for personalized treatment strategies. CLINICAL RELEVANCE: These findings validate bridging plate reconstruction as a safe and pragmatic alternative for patients with contraindications to osseous flaps, such as advanced age or significant comorbidities. The comparable complication rates and shorter operative times support its use in personalized treatment planning.

Indexed as

Bone PlatesFree Tissue FlapsMandibular ReconstructionPostoperative ComplicationsAgedBone TransplantationFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcome3D-printed osteosynthesisCustomized mandibular implantDental rehabilitationMandibulectomyMicrovascular reconstructionPatient-specific reconstruction

Identifiers

PMID41546715
PMCPMC12812072

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.