Evidence map›Paper›PMID 41546622›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2026

Atrial fibrillation ablation using three-dimensional artificial intelligence module integration with intracardiac echocardiography.

Fengwei Zou, Sarah Xu, Sanjana Nagraj, Sheetal Mathai, Ariel Gidon, Nay Yee Wint Kyaw, Jose Matias, Giuseppe Ammirati, Jacopo Marazzato, Aung Lin and 8 more

Abstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Intracardiac Echocardiography during Invasive Electrophysiological Procedures: a Scientific Statement of the European Heart Rhythm Association of the ESC, and the European Association of Percutaneous Cardiovascular Interventions of the ESC.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Guideline
  2. Pooled it
  3. Artificial intelligence-intracardiac echocardiography-guided pulsed field ablation of atrial fibrillation with variable-loop circular catheter.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  4. Article
  5. Atrial fibrillation ablation using three-dimensional artificial intelligence module integration with intracardiac echocardiography.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Fengwei ZouMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0001-6355-8843
Sarah XuMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0009-0001-2668-4055
Sanjana NagrajMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0002-6230-7214
Sheetal MathaiMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0002-3254-4841
Ariel GidonMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0009-0001-4658-0990
Nay Yee Wint KyawMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.
Jose MatiasMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0001-7614-2118
Giuseppe AmmiratiMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0002-7440-1793
Jacopo MarazzatoMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0003-1205-5925
Aung LinMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0002-8624-7084
Domingo Y YnoaMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.
Marco SchiavoneCentro Cardiologico Monzino, IRCCS, Milan 20138, Italy.ORCID 0000-0003-0720-3380
Vincenzo Mirco La FaziaTexas Cardiac Arrhythmias Institute, St. David's Medical Center, Austin, TX 78705, USA.ORCID 0000-0001-7548-4685
Sanghamitra MohantyTexas Cardiac Arrhythmias Institute, St. David's Medical Center, Austin, TX 78705, USA.ORCID 0000-0002-5487-0728
Andrea NataleTexas Cardiac Arrhythmias Institute, St. David's Medical Center, Austin, TX 78705, USA.ORCID 0000-0001-6601-944X
Pasquale SantangeliCardiac Electrophysiology and Pacing, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-0023-9666
Xiaodong ZhangMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0002-2856-943X
Luigi Di BiaseMontefiore Einstein Center for Heart & Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th Street, Bronx, NY 10467, USA.ORCID 0000-0001-6508-4047

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsIntracardiac echocardiography-based electroanatomical mapping (EAM) improves procedural efficiency and safety in atrial fibrillation (AF) ablation and remains the standard of care. The CARTOSOUND FAM (AI FAM) module uses a deep-learning algorithm that automates left atrial reconstruction without manual contouring. This study aims to evaluate the 1-year outcomes of AI FAM compared to standard-of-care EAM in AF ablation. METHODS AND

resultsThis study included 298 patients undergoing radiofrequency AF ablation between January 2021 and December 2023. Patients treated before January 2023 underwent standard-of-care EAM, while those in 2023 utilized AI FAM-based reconstruction. Baseline demographics, comorbidities, AF type, and medication use were recorded. Procedural characteristics, acute success, complications, and AF recurrence at 1-year follow-up were analysed. Of the 298 patients, 115 underwent mapping with AI FAM and 183 with EAM. Baseline characteristics were comparable. AI FAM reduced mean total procedure time (122.5 ± 23.5 vs. 129.0 ± 30.4 min, P = 0.040) and left atrial (LA) dwell time (78.3 ± 21.45 vs. 87.5 ± 28.2 min, P = 0.001). Acute procedural success was 98.3% in AI FAM vs. 98.9% in EAM with fewer complications observed in the AI FAM group (1 vs. 4). At 1 year, freedom from AF recurrence was comparable (80.0% AI FAM vs. 81.4% EAM at 1 year, LogRank P = 0.610).

conclusionAI FAM was associated with incremental but significant procedural advantages over conventional contouring via reduced total procedure time and LA dwell time, without compromising acute and long-term safety and rhythm control efficacy. AI FAM integration with pulsed field ablation will mark another step towards making AF ablation more streamlined and accessible.

Indexed as

Artificial IntelligenceAtrial FibrillationCatheter AblationEchocardiographyEchocardiography, Three-DimensionalSurgery, Computer-AssistedAgedFemaleHeart AtriaHumansIntelligent SystemsMaleMiddle AgedRecurrenceRetrospective StudiesTreatment OutcomeArtificial intelligenceAtrial fibrillationCARTOSOUND FAMCatheter ablationElectroanatomical mappingIntracardiac echocardiography

Identifiers

PMID41546622
PMCPMC12950898

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.