Evidence map›Paper›PMID 41546493›Full record

ArticleVeterinary pathology2026

Morphological characterization of a novel model of steatohepatitis in the

Silvana N Wilken, Philipp Felgendreff, Anna Minshew, Boyukkhanim Ahmadzada, Seyed M Hosseiniasl, Sara Kazeminia, Kachi Ezenekwe, Ameya Patil, Byoung U Park, Ahmer Sultan and 6 more

Abstract read
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In one paragraph

Article in Veterinary pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Silvana N WilkenMayo Clinic, Rochester, MN.ORCID 0009-0004-9168-4950
Philipp FelgendreffMayo Clinic, Rochester, MN.
Anna MinshewMayo Clinic, Rochester, MN.
Boyukkhanim AhmadzadaMayo Clinic, Rochester, MN.
Seyed M HosseiniaslMayo Clinic, Rochester, MN.
Sara KazeminiaMayo Clinic, Rochester, MN.ORCID 0000-0002-2621-9962
Kachi EzenekweMayo Clinic, Rochester, MN.
Ameya PatilMayo Clinic, Rochester, MN.
Byoung U ParkUniversity of Minnesota, Minneapolis, MN.ORCID 0000-0002-8797-2026
Ahmer SultanMayo Clinic, Rochester, MN.
Lindsey SmithMysSME LLC, Birmingham, AL.
Julio Cisneros CorreaMayo Clinic, Rochester, MN.
Kamal HusseinMayo Clinic, Rochester, MN.
Harmeet MalhiMayo Clinic, Rochester, MN.
Roger K MoreiraMayo Clinic, Rochester, MN.
Scott L NybergMayo Clinic, Rochester, MN.ORCID 0000-0002-5005-3050

Funding

Pathobiology of Liver InjuryR01DK111378 · NIDDK · MAYO CLINIC ROCHESTER · PI MALHI, HARMEET · 2016 to 2025
$3.9M
Immunodeficient FAH-/- PigsR01DK106667 · NIDDK · MAYO CLINIC ROCHESTER · PI NYBERG, SCOTT L · 2015 to 2019
$2.1M
NIDDK NIH HHS R01 DK106667NIDDK NIH HHS R01 DK111378
6 · The paper itself

Abstract

Metabolic dysfunction-associated steatohepatitis (MASH) is a global health care burden. Appropriate large animal models mimicking the main MASH characteristics of steatosis, inflammation, and hepatocyte damage alongside progression of fibrosis are imperative for robust preclinical studies, especially in the field of hepatobiliary surgery. The present study aimed to characterize a novel model of steatohepatitis in fumarylacetoacetate hydroxylase-deficient (

Indexed as

Disease Models, AnimalFatty LiverAnimalsDiet, High-FatFemaleInflammationLiverLiver CirrhosisMaleSwineCDAHFDFAH deficiencyfibrosishepatic steatosisliverMASHporcine modelsteatohepatitis

Identifiers

PMID41546493
PMCPMC13198166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.