Evidence map›Paper›PMID 41546089›Full record

ArticleNutrition & metabolism2026

Characterization of avocado seeds aqueous extract and its therapeutic effects on gastric ulcer.

Aroosa Sultan, Muhammad Nadeem Akhtar, Anees Ahmed Khalil, Faiza Jameel, Suhas Ballal, Abhayveer Singh, Rajashree Panigrahi, Abhishek Sharma, Huda Ateeq, Areesha Ahmed and 3 more

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Article in Nutrition & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aroosa SultanUniversity Institute of Diet and Nutritional Sciences, University of Lahore, Lahore, Pakistan.
Muhammad Nadeem AkhtarUniversity Institute of Diet and Nutritional Sciences, University of Lahore, Lahore, Pakistan.
Anees Ahmed KhalilUniversity Institute of Diet and Nutritional Sciences, University of Lahore, Lahore, Pakistan.
Faiza JameelDepartment of Food Science, Government College University Faisalabad, Faisalabad, Pakistan.
Suhas BallalDepartment of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
Abhayveer SinghSharda School of Pharmacy, Sharda University, Greater Noida, 140401, Punjab, India.
Rajashree PanigrahiDepartment of Microbiology, IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, 751003, Odisha, India.
Abhishek SharmaDepartment of Medicine, National Institute of Medical Sciences, NIMS University Rajasthan, Jaipur, India.
Huda AteeqUniversity Institute of Food Science and Technology, The University of Lahore, Lahore, Pakistan.
Areesha AhmedNur Institute of Food Sciences, NUR International University, Lahore, Pakistan.
Fakhar IslamDepartment of Food Science, Government College University Faisalabad, Faisalabad, Pakistan.
Muhammad AfzaalDepartment of Food Science, Government College University Faisalabad, Faisalabad, Pakistan.
Catherine Tamale NdagireDepartment of Food Innovation and Nutrition, Mountains of the Moon University, Fort Portal, Uganda. catherinendagire@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHelicobacter pylori infection and oxidative stress are most common factors for development of gastric ulcers which is consider to be a most common gastrointestinal disorder. The main objective of this research was to evaluate the effects of avocado seeds aqueous extract as an adjunct to conventional ulcer treatment.

methodsA randomized controlled trial was conducted with the participation of 99 patients diagnosed with gastric ulcers. Participants were randomly divided to a control group receiving standard medication and interventional group receiving the same treatment with avocado seeds aqueous extract. Screening and follow-up assessments assessment was performed by barium meal tests, radiological imaging, and serological markers, including H. pylori IgG and IgM (ELISA).

resultsPatients in the intervention group showed significant improvements in ulcer morphology and a marked reduction in H. pylori IgG and IgM levels compared with the control group (p < 0.05). Radiological findings also confirmed better mucosal healing in the supplemented group after 12 weeks of intervention.

conclusionsIntervention group with avocado seeds aqueous extract showed a positive effect combined with conventional treatment, suggesting its potential as a natural adjunct therapy in management of gastric ulcers.

Indexed as

AvocadoAvocado seedsBarium mealGastric ulcersHelicobacter pylori

Identifiers

PMID41546089
PMCPMC12895594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.