Evidence map›Paper›PMID 41546059›Full record

ArticleBreast cancer research : BCR2026

[

Anjong Florence Tikum, Dede Api Fon, Fabrice Ngoh Njotu, Nikita Henning, Emmanuel Nwangele, Hanan Babeker, Jessica Pougoue Ketchemen, Alireza Doroudi, Maruti Uppalapati, Humphrey Fonge

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Breast cancer research : BCR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anjong Florence TikumDepartment of Medical Imaging, College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada.
Dede Api FonFaculté de Pharmacie, Université Laval, Ferdinand Vandry Pavillon, Québec, QC, G1V 0A6, Canada.
Fabrice Ngoh NjotuFaculté de Pharmacie, Université Laval, Ferdinand Vandry Pavillon, Québec, QC, G1V 0A6, Canada.
Nikita HenningDepartment of Medical Imaging, College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada.
Emmanuel NwangeleFaculté de Pharmacie, Université Laval, Ferdinand Vandry Pavillon, Québec, QC, G1V 0A6, Canada.
Hanan BabekerDepartment of Medical Imaging, College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada.
Jessica Pougoue KetchemenFaculté de Pharmacie, Université Laval, Ferdinand Vandry Pavillon, Québec, QC, G1V 0A6, Canada.
Alireza DoroudiDepartment of Medical Imaging, College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada.
Maruti UppalapatiDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 5E5, Canada.
Humphrey FongeDepartment of Medical Imaging, College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada. humphrey.fonge@crchudequebec.ulaval.ca.ORCID http://orcid.org/0000-0001-9388-6872

Funding

CIHR 437660Fond de la Recherche de Quebec (FRQ) 30641
6 · The paper itself

Abstract

backgroundEGFR is overexpressed in TNBC, and "naked" anti-EGFR monoclonal antibodies have been evaluated in clinical trials with dismal effectiveness. Matuzumab is an anti-EGFR monoclonal antibody that can be used to develop theranostics. We posit that compared with "naked" antibodies, [

methodsWe developed and characterized [

resultsBiodistribution of [

conclusion[

Indexed as

Antibodies, Monoclonal, HumanizedRadioimmunotherapyTriple Negative Breast NeoplasmsActiniumAnimalsCell Line, TumorErbB ReceptorsFemaleHumansMDA-MB-231 CellsMiceMice, Inbred BALB CMice, NudeTissue DistributionXenograft Model Antitumor AssaysActiniumActinium-225Antibodies, Monoclonal, HumanizedEGFR protein, humanErbB ReceptorsmatuzumabActinium-225Alpha particle therapyEGFRRadioimmunotherapyTNBC

Identifiers

PMID41546059
PMCPMC12892558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.