Evidence map›Paper›PMID 41545977›Full record

ArticleBMC surgery2026

Surgical treatment for neurofibromatosis type 1-related dystrophic scoliosis in children aged 8 to 11: traditional growing rod or posterior spinal fusion?

Haichong Li, Hanwen Zhang, Rongxuan Gao, Haonan Liu, Dong Guo, Jun Cao, Xuejun Zhang, Ziming Yao

Abstract readComparative Study
In one paragraph

Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haichong LiDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China.
Hanwen ZhangDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China.
Rongxuan GaoDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China.
Haonan LiuDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China.
Dong GuoDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China.
Jun CaoDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China.
Xuejun ZhangDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China.
Ziming YaoDepartment of Orthopaedics, Beijing Children's Hospital, National Center for Children's Health, Beijing, 100045, China. docyao@mail.ccmu.edu.cn.

Funding

Key R&D Program of Xinjiang 2023 B03018-2National Key R&D Program of China 2023YFC2507701
6 · The paper itself

Abstract

backgroundTo compare the clinical outcomes of posterior spinal fusion (PSF) and traditional growing rod (TGR) surgery for neurofibromatosis type 1-associated dystrophic scoliosis (NF1-DS) in children aged 8–11 years. The aim is also to identify the factors that influence surgical selection and spinal growth.

methodsPatients with NF1-DS and major thoracic curves involving at least five vertebral levels were enrolled and divided into PSF and TGR groups. Demographic, radiographic and surgical data were analyzed for both a 1:1 propensity score-matched cohort (n = 26) and the full cohort (n = 39). Logistic regression was used to identify factors influencing surgical selection, and Spearman correlation was used to analyze spinal growth predictors.

resultsPSF achieved greater initial curve correction than TGR (61.0% vs. 47.0%, p = 0.025; 58.0% vs. 52.0%, p = 0.015), though there was no difference at the final follow-up. TGR showed greater thoracic (5.2–5.6 cm vs. 3.4–3.5 cm) and spinal height gains (9.0–10.3 cm vs. 4.6–4.9 cm). TGR required more surgeries (5.0 vs. 1.0, p = 0.001), but complication rates were similar. Initial apical vertebra translation (AVT) independently guided surgical selection: PSF for AVT < 46.6 mm and TGR for AVT > 46.6 mm. In the TGR group, greater spinal growth positively correlated with initial curve magnitude, coronal balance, and AVT, while in the PSF group, it positively correlated with the initial main curve correction rate.

conclusionsThis study provides clinical evidence to guide surgical decision-making for 8-11-year-old patients with NF1-DS.

Indexed as

Neurofibromatosis 1ScoliosisSpinal FusionChildFemaleHumansMaleRetrospective StudiesThoracic VertebraeTreatment OutcomeNeurofibromatosis type 1Posterior spinal fusionScoliosisTraditional growing rod

Identifiers

PMID41545977
PMCPMC12896003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.