ArticleEuropean journal of medical research2026
Preoperative black line sign predicts progressive kyphosis after percutaneous kyphoplasty in osteoporotic vertebral compression fractures.
Article in European journal of medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesThis study aimed to evaluate the black line sign (BLS) on preoperative MR-STIR images as a predictor of progressive kyphosis (PK) following percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs). The goal of this study was to assess its significance in identifying patients at greater risk for postoperative kyphotic deformities and to refine clinical management strategies.
methodsThis single-center retrospective study analyzed 182 patients with OVCFs who underwent PKP between January 2019 and December 2022. Patients were categorized into two groups based on the presence or absence of BLS on preoperative MRI: the BLS group and the non-black line sign (NBLS) group. Radiological and clinical outcomes were compared between these two groups. Both univariate and multivariate analyses were performed to identify risk factors associated with the development of PK.
resultsAt the 1-year follow-up, the BLS group presented significantly greater vertebral height loss and kyphotic angle differences than did the NBLS group. Furthermore, the visual analog scale and Oswestry Disability Index scores were notably higher in the BLS group (P < 0.001). The incidence of PK in the BLS group was 75.0% (39/52), which was significantly greater than the 16.2% (21/130) observed in the NBLS group (P < 0.001). Cumulative event analysis revealed that a greater proportion of patients in the BLS group developed PK over the follow-up period. Both the log-rank test and Cox regression analysis demonstrated statistically significant differences (P < 0.001). Multivariate regression analysis revealed that BLS was a significant independent risk factor for PK, with an odds ratio of 9.827 (P < 0.001).
conclusionsThe black line sign on preoperative MR-STIR images is a significant predictor of PK after PKP for OVCFs. Clinicians should consider closer monitoring, external bracing, and aggressive osteoporosis treatment for patients with BLS to reduce the risk of postoperative kyphotic deformities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.