Evidence map›Paper›PMID 41545807›Full record

ArticleArchives of gynecology and obstetrics2026

Radiofrequency ablation for giant congenital lung malformations complicated by fetal hydrops: a retrospective case series.

Feng Qin, Ting Huang, Xuegang Luo, Wenfei Luo, Xiaochuan Xu, Yong Yang, Xiaoyan Chen, Xingbo Tian, Dianhong Kang, Yamin Liu and 1 more

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In one paragraph

Article in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Feng QinFetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Ting Huang *Fetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Xuegang LuoFetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Wenfei LuoUltrasound Department, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Xiaochuan XuFetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Yong YangFetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Xiaoyan ChenFetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Xingbo TianFetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Dianhong KangUltrasound Department, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Yamin Liu *Fetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
Gongli ChenFetal Medicine Center, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China. chengongli@cqmu.edu.cn.

Funding

National Key Research and Development Program of China 2023YFC2705904
6 · The paper itself

Abstract

objectiveTo evaluate the surgical efficacy and prognosis of radiofrequency ablation (RFA) in the treatment of microcystic congenital pulmonary airway malformation (CPAM) complicated by fetal hydrops, with the CLM volume ratio (CVR) exceeding 2.0 and refractory to conservative treatment with maternal steroid administration.

methodsWe collected data from fetal microcystic CPAM cases with CVR > 2.0, complicated by fetal hydrops, and refractory to maternal steroid therapy, who underwent RFA at our hospital from June 2020 to June 2024.

resultsThe study comprised five fetuses, all diagnosed with microcystic CPAM complicated by fetal hydrops. All fetuses had a mean CVR of 3.8 (range, 2.2-5.3) and were complicated by fetal hydrops. All cases received two courses of maternal steroid before the RFA procedure. Among the five cases, three newborns were delivered at a mean gestational age of 36.6 weeks (range 35.2-38.7 weeks), and two cases of IUFD occurred postoperatively.

conclusionFor microcystic CPAM complicated with fetal hydrops and refractory to maternal conservative steroid administration, ultrasound-guided RFA serves as an effective salvage option for intrauterine treatment. Nevertheless, intrauterine interventional procedures should be performed with extreme caution, given the potential risks of IUFD.

Indexed as

Cystic Adenomatoid Malformation of Lung, CongenitalHydrops FetalisRadiofrequency AblationAdultFemaleGestational AgeHumansInfant, NewbornPregnancyRetrospective StudiesTreatment OutcomeUltrasonography, PrenatalBronchopulmonary sequestrationCLM volume ratioCongenital pulmonary airway malformationCyst aspirationRadiofrequency ablation

Identifiers

PMID41545807
PMCPMC12811271

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.