Evidence map›Paper›PMID 41545633›Full record

Trial reportOdontology2026

PRF membrane vs. chorion membrane with coronally advanced flap: a clinical study on gingival recession.

Bimmi Tripathi, R G Shiva Manjunath, Jaishree Garg, Shankar T Gokhale, Raghavendra Reddy Nagate, K Nishant, Saad M Al-Qahtani, Mohammad Al Magbol, Shreyas Tikare, Mudita Chaturvedi and 4 more

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07308405 (Comparative Clinical Evaluation of Coronally Advanced Flap With Platelet Rich Fibrin Membrane and Chorion Membrane in the Treatment of Human Gingival Recession), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07308405 nacompletednot on this map

Comparative Clinical Evaluation of Coronally Advanced Flap With Platelet Rich Fibrin Membrane and Chorion Membrane in the Treatment of Human Gingival Recession

TypeinterventionalSponsorInstitute of Dental Sciences, Bareilly, Uttar Pradesh, IndiaRan2015 to 2016Enrolled50ConditionsGingival RecessionArmsCoronally advanced flap (CAF) with platelet-rich fibrin (PRF), A similar surgical procedure was followed for the recipient bed preparation similar to that for the PRF membrane. A chorion membrane (Tissue bank, Tata Memorial Hospital, Mumbai, Maharashtra, India) o
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bimmi TripathiDepartment of Periodontics and Implantology, Peoples College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
R G Shiva ManjunathDepartment of Periodontics and Implantology, Dental Institute-RIMS, Bariatu, Ranchi, Jharkhand, 834009, India.
Jaishree GargDepartment of Periodontics and Implantology Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.
Shankar T GokhaleDepartment of Oral Diagnosis, Oral Biology and Periodontology, Division of Periodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Raghavendra Reddy NagateDepartment of Oral Diagnosis, Oral Biology and Periodontology, Division of Periodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
K NishantDepartment of Oral and Maxillofacial Pathology, UCMS College of Dental Surgery, Bhairahawa, Nepal. drnishantop@gmail.com.ORCID http://orcid.org/0000-0002-6770-4067
Saad M Al-QahtaniDepartment of Oral Diagnosis, Oral Biology and Periodontology, Division of Periodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Mohammad Al MagbolDepartment of Oral Diagnosis, Oral Biology and Periodontology, Division of Periodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Shreyas TikareDepartment of Oral Diagnosis, Oral Biology and Periodontology, Division of Periodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Mudita ChaturvediDepartment of Dental Research Cell, Dr. Y. Patil Dental College and Hospital, Dr. Y. Patil Vidyapeeth, Sant-Tukaram Nagar, Pimpri, Pune, 411018, India.
Mohammed A Al-QarniConsultant in Restorative Dentistry, College of Dentistry, King Khalid University, P. O. Box 3263, 61471, Abha, Saudi Arabia.
Mohamed Fadul A ElagibDepartment of Oral Diagnosis, Oral Biology and Periodontology, Division of Periodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Mukhatar Ahmed JavaliDepartment of Oral Diagnosis, Oral Biology and Periodontology, Division of Periodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Saurabh ChaturvediDepartment of Prosthetic Dentistry, College of Dentistry King, Khalid University, Abha, Saudi Arabia.

Funding

Deanship of Scientific Research, King Khalid University RGP1/134/46
6 · The paper itself

Abstract

Platelet-rich fibrin (PRF), a second-generation platelet concentrate, accelerates soft and hard tissue regeneration. Chorion membrane, of fetal origin, has wound-modulating properties. This study aimed to evaluate and compare the clinical outcomes of PRF and chorion membrane in treating isolated Miller's class I or II gingival recession defects. Fifty recession defects in 50 patients were randomly treated with a coronally advanced flap (CAF) and PRF membrane (site A, n = 25) or CAF with chorion membrane (site B, n = 25). Clinical parameters recorded at baseline, 1, 3, and 6 months included recession depth (RD), recession width (RW), clinical attachment level (CAL), width of keratinized gingiva (WKG), plaque index (PI), gingival index (GI), and gingival biotype. Statistical analysis compared outcomes across follow-up intervals. At 6 months, both groups demonstrated significant improvements in RD, RW, CAL, WKG, PI, and GI compared with baseline. Mean percentage root coverage was 86.76 ± 13.76 in the PRF group and 82.89 ± 15.65 in the chorion group, with no statistically significant difference between them. Sites with an initial thin biotype showed conversion to thick biotype in both groups. Both PRF and chorion membrane demonstrated predictable effectiveness for managing isolated recession defects, with comparable outcomes. Longitudinal studies are needed to confirm these findings.

trial registration(Clinical trial number- NCT07308405).

Indexed as

ChorionGingival RecessionPlatelet-Rich FibrinSurgical FlapsAdultFemaleHumansMaleMiddle AgedTreatment OutcomeChorion membraneCoronally advanced flapFibrinGingival recession defectPlatelet-richRoot coverage

Identifiers

PMID41545633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.