Evidence map›Paper›PMID 41545480›Full record

ArticleScientific reports2026

Interspecies scaling of suprachoroidal drug delivery using ocular geometry and drug physicochemical properties.

Madhoosudan A Patil, Brock A Matter, Cleildo Santana, Uday B Kompella

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Madhoosudan A PatilDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, C238-V20, Aurora, CO, USA.
Brock A MatterDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, C238-V20, Aurora, CO, USA.
Cleildo SantanaDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, C238-V20, Aurora, CO, USA.
Uday B KompellaDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, C238-V20, Aurora, CO, USA. uday.kompella@cuanschutz.edu.

Funding

Suprachroidal Drug Delivery for Retina DisordersR01EY022097 · NEI · UNIVERSITY OF COLORADO DENVER · PI KOMPELLA, UDAY B, PRAUSNITZ, MARK R. · 2013 to 2016
$2.3M
NEI NIH HHS R01 EY022097NIH grant R01EY022097
6 · The paper itself

Abstract

Excised rabbit, porcine, and bovine eyes were injected in the suprachoroidal space with a cassette of 27 drugs, including 10 beta-blockers, 8 NSAIDs, and 9 corticosteroids, spanning a lipophilicity range (LogD

Indexed as

ChoroidDrug Delivery SystemsEyeRetinaVitreous BodyAdrenal Cortex HormonesAnimalsAnti-Inflammatory Agents, Non-SteroidalCattleRabbitsSpecies SpecificitySwineTandem Mass SpectrometryAdrenal Cortex HormonesAnti-Inflammatory Agents, Non-SteroidalBeta blockersCorticosteroidsDrug cassetteNSAIDsOcular drug deliverySuprachoroidal delivery

Identifiers

PMID41545480
PMCPMC12864957

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.