Evidence map›Paper›PMID 41545444›Full record

ArticleNPJ science of food2026

Structural divergence of lentinula edodes polysaccharides is associated with distinct anti-hyperuricemia pathways.

Xinyi Xiong, Peng Liu, Liping Liu, Jie Feng, Jingsong Zhang, Jinyan Wang, Jie Geng, Yanfang Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinyi XiongInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China.
Peng LiuInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China.
Liping LiuInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China.
Jie FengInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China.
Jingsong ZhangInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China.
Jinyan WangInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China.
Jie GengInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China.
Yanfang LiuInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture and Rural Affairs, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, China. aliu-1980@163.com.

Funding

Shanghai Academy of Agricultural Sciences (SAAS) Program for Excellent Research Team G2022003Shanghai Agriculture Applied Technology Development Program, China T2023109the Earmarked Fund for China Agriculture Research System, China CARS-20
6 · The paper itself

Abstract

Lentinula edodes (L. edodes) polysaccharides hold therapeutic potential for hyperuricemia (HUA), but their mechanisms remain unclear. This study investigated the anti-HUA effects and associated regulatory pathways of two structurally distinct polysaccharides (LEP20 and LEP50) from L. edodes. Structural analysis identified LEP20 as a (1 → 3)-β-D-glucan (M

Identifiers

PMID41545444
PMCPMC12909888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.