ArticleNature communications2026
Near-infrared light-driven nanomotors-based microneedles for the active therapy of bacterial infected acne.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Destroy and reconstruct: A microneedle platform for combined NIR-II photothermal therapy and asiaticoside-mediated tissue regeneration in cutaneous amyloidosis.Materials today. Bio · 2026Article
- Metal oxide nanoparticles for acne vulgaris: mechanisms, synthesis, formulation, and translational prospects.RSC advances · 2026Review
- Simultaneous broad-spectrum antibacterial and regenerative therapy for diabetic wounds using sonosensitive peptide composite hydrogel.Journal of nanobiotechnology · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Acne, caused by Cutibacterium acnes, triggers inflammatory lesions. The hypoxic biofilm microenvironment exacerbates acne progression, while inadequate hydrogen peroxide and dense biofilm barriers hinder oxygen generation and nanomedicine penetration. Here, we develop microneedles patch loaded with near infrared-driven self-oxygenating Z@P-M nanomotors for photothermal therapy of acne. Zinc peroxide nanoparticles are asymmetrically modified with polydopamine, followed by in-situ manganese dioxide growth on polydopamine to form Z@P-M nanomotors. Z@P-M nanomotors loaded microneedles penetrate the stratum corneum to deliver antibacterial nanoparticles into the dermis. In female murine acne, Zinc peroxide slowly releases hydrogen peroxide in acidic biofilm, catalyzed by manganese dioxide to generate oxygen, thus alleviating hypoxia and skin inflammation. After near infrared laser irradiation, the thermal gradient generated by the asymmetrically modified polydopamine coating endows the nanomotors with enhanced diffusion to promote biofilm penetration, further improving photothermal therapy efficacy and showing a potential for active acne treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.