Evidence map›Paper›PMID 41545367›Full record

ArticleScientific reports2026

Comparative chemical and biological study of essential oils and n-hexane extracts of Thymus vulgaris and Thymus serpyllum (Lamiaceae).

Mohamed M M AbdelRazek, Asmaa M Atta, Nariman H Kandil, Iriny E G Girgis, Rana T O Elsayed, Bassant R M Abdel-Latif, Asmaa E Abdel-Halim, Shada G I Salama, Tag El-Din M Ahmed, Mennat Allah S AbdelRazek and 8 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Mohamed M M AbdelRazekDepartment of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt. mohamed.abdelrazek@buc.edu.eg.
Asmaa M AttaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr, 11829, Cairo, Egypt.
Nariman H KandilDepartment of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Iriny E G GirgisInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Rana T O ElsayedInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Bassant R M Abdel-LatifInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Asmaa E Abdel-HalimInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Shada G I SalamaInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Tag El-Din M AhmedInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Mennat Allah S AbdelRazekInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Fady H FoadInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Rodaina M S ElsayedInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Sara H E AslanInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Nada I E BadawyInternship Researcher, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Engy A FaroukDepartment of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Sara A OmranDepartment of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.
Khaled M DarwishDepartment of Medicinal Chemistry, Faculty of Pharmacy, Galala University, New Galala, 43713, Egypt.
Safaa A El-MoghazyDepartment of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a comparative chemical and biological evaluation of essential oils (EOs) and n-hexane extracts from Thymus vulgaris and Thymus serpyllum (Lamiaceae), alongside a reference commercial thyme oil. GC-MS analysis revealed significant differences in chemical composition among the samples, with T. serpyllum oil characterized by high thymol (74.47%) and caryophyllene (9.89%) content, while the commercial oil was dominated by carvacrol (80.37%). Cytotoxicity was assessed using the sulforhodamine B (SRB) assay on human skin fibroblast (HSF) cells to evaluate safety. Most samples exhibited low cytotoxicity (IC

Indexed as

HexanesOils, VolatilePlant ExtractsThymus PlantCell LineCymenesFibroblastsGas Chromatography-Mass SpectrometryHumansHypoglycemic AgentsMolecular Docking SimulationPolycyclic SesquiterpenesThymolWound HealingWounds and InjuriescarvacrolcaryophylleneCymenesHexanesHypoglycemic Agentsn-hexaneOils, VolatilePlant ExtractsPolycyclic SesquiterpenesThymolEssential oilGC-MSMolecular dockingn-hexane extractThymusWound healing

Identifiers

PMID41545367
PMCPMC12819475

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.