Evidence map›Paper›PMID 41543990›Full record

ArticleEuropean addiction research2026

Confidence in Managing Use and Minimising Harm as Mediators of Quality of Life among Anabolic-Androgenic Steroid Consumers in Alcohol and Other Drug Treatment Settings.

Benjamin Bonenti, Nicholas Leigh Kerswell, Grace Shuttleworth, Carmen Lim, Thomas O'Connor, Jason Ferris, Kylie Lee, Timothy Piatkowski

Abstract read
In one paragraph

Article in European addiction research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin BonentiSchool of Applied Psychology and Griffith Centre for Mental Health, Griffith University, Brisbane, Queensland, Australia, b.bonenti@griffith.edu.au.
Nicholas Leigh KerswellLives Lived Well, Brisbane, Queensland, Australia.
Grace ShuttleworthLives Lived Well, Brisbane, Queensland, Australia.
Carmen LimNational Centre for Youth Substance Use, University of Queensland, Brisbane, Queensland, Australia.
Thomas O'ConnorDepartment of Internal Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Jason FerrisCentre for Health Services Research, University of Queensland, Brisbane, Queensland, Australia.
Kylie LeeCentre for Alcohol Policy Research, La Trobe University, Melbourne, Victoria, Australia.
Timothy PiatkowskiSchool of Applied Psychology and Griffith Centre for Mental Health, Griffith University, Brisbane, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Anabolic-androgenic steroid (AAS) consumers frequently experience elevated physical and psychological risks, yet the psychological mechanisms linking risk exposure to health outcomes remain poorly understood. This study examined whether general confidence in managing substance use and minimising harm mediates the relationship between clinical risk and quality of life among AAS consumers engaged with community-based alcohol and other drug (AOD) services.

methodsIntake data from 517 adults (93.4% male) reporting lifetime AAS use were analysed, drawn from a broader cohort of 18,786 clients at Lives Lived Well services between 2020 and 2024. Mediation analyses tested whether two confidence variables: (1) substance use management and (2) harm minimisation, explained associations between clinical risk (defined by World Health Organisation - Alcohol, Smoking and Substance Involvement Screening Test steroid risk score), and three quality of life domains: physical, psychological, and overall wellbeing.

resultsHigher clinical steroid risk scores were significantly associated with poorer quality of life across domains; however, these effects were fully mediated by lower general confidence in managing substance use and minimising harm among clients who reported AAS use. Confidence in consumption practices buffered against physical undesired effects, while confidence in harm reduction was strongly linked to psychological wellbeing.

conclusionsAmong AAS consumers in AOD treatment, broader substance use confidence appears meaningfully related to quality of life. While the confidence measures are general rather than AAS-specific, these findings provide a preliminary insight into confidence-related processes in a clinically underexamined group. Interventions that promote these strategies may offer a critical mechanism for ensuring this cohort physical and psychological wellbeing. </p>.

Indexed as

Anabolic AgentsHarm ReductionQuality of LifeSubstance-Related DisordersAdultAnabolic Androgenic SteroidsFemaleHumansMaleMiddle AgedYoung AdultAnabolic AgentsAnabolic Androgenic SteroidsAnabolic-androgenic steroidsClinical riskConfidenceHarm reductionHealth educationHealth literacyQuality of life

Identifiers

PMID41543990
PMCPMC12912760

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.