ArticleIEEE transactions on medical imaging2026
A High-Performance Self-Collimation SPECT for Small Animal Imaging.
Article in IEEE transactions on medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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18 authors.
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Abstract
Stemmed from our novel single-photon imaging concept of detector self-collimation-which leverages detectors themselves as collimators to overcome the inherent resolution-sensitivity trade-off in conventional SPECT-this study presents the design and evaluation of the first full-ring self-collimation SPECT (SC-SPECT) scanner for small animal imaging. The system features four concentric detector rings and two interchangeable high-aperture-ratio tungsten collimator rings optimized for high-resolution (HR) and general-purpose (GP) imaging applications. Detector rings contain 480, 720, 960, and 1,200 evenly distributed GAGG(Ce) scintillators, each measuring 0.84 mm (tangential) $\times 6$ mm (radial) $\times 20$ mm (axial) and separated by 0.84-mm gaps to enable effective photon collimation. Inner detector rings and the collimator ring collectively provide collimation for photons reaching subsequent outer rings. Dual-end SiPM readouts facilitate axial depth-of-interaction measurements. Phantom and mouse studies are performed to assess the system's resolution, sensitivity, and field-of-view volume, and SC-SPECT demonstrates generally superior performance compared with state-of-the-art small-animal SPECT systems. Mouse bone images using
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