The Impact of Ancestry on Performance of Type 1 Diabetes Genetic Risk Scores: High Discrimination Performance Is Maintained in African Ancestry Populations, but Population-Specific Thresholds May Improve Risk Prediction.
Article in Diabetes care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Steven SquiresClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.ORCID 0000-0003-3681-1342
Jean Claude KatteClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.ORCID 0000-0001-5631-2810
Dana DabeleaLifecourse Epidemiology of Adiposity and Diabetes Center Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0001-9514-8929
Jasmin DiversDepartment of Foundations of Medicine, NYU Grossman Long Island School of Medicine, Mineola, NY.
Eugene SobngwiDepartment of Internal Medicine and Specialities, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.ORCID 0000-0001-5457-6572
Moffat J NyirendaNon-Communicable Diseases Theme, Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.ORCID 0000-0003-2120-4806
Raymond J KreienkampBoston Children's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-1683-323X
Angela D LieseArnold School of Public Health, University of South Carolina, Columbia, SC.ORCID 0000-0002-7022-0178
Amy S ShahCincinnati Children's Hospital Medical Center, The University of Cincinnati, Cincinnati, OH.ORCID 0000-0001-7297-139X
Lawrence DolanCincinnati Children's Hospital Medical Center, The University of Cincinnati, Cincinnati, OH.
Kristi ReynoldsDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA.ORCID 0000-0001-7619-1649
Maria J RedondoTexas Children's Hospital, Baylor College of Medicine, Houston, TX.ORCID 0000-0001-5871-4645
William HagopianPacific Northwest Diabetes Research Institute, University of Washington, Seattle, WA.ORCID 0000-0003-2979-0475
Segun FatumoPrecision Healthcare University Research Institute, Queen Mary University of London, London, U.K.
Mesmin Y DehayemNational Obesity Centre and the Endocrinology and Metabolic Diseases Unit, Yaoundé Central Hospital, Yaoundé, Cameroon.
Andrew T HattersleyClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.ORCID 0000-0001-5620-473X
Michael N WeedonClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.ORCID 0000-0002-6174-6135
Angus JonesClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.ORCID 0000-0002-0883-7599
Richard A OramClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.ORCID 0000-0003-3581-8980
Funding
Diabetes-Docs: Physician-Scientist Career Development Program (DiabDocs)K12DK133995 · NIDDK · STANFORD UNIVERSITY · PI LINDA A DIMEGLIO, David Matthew Maahs · 2022 to 2026
$16.0M
Type 1 diabetes genetic risk scores for the diagnosis of diabetes type in children of diverse racial and ethnic backgroundR01DK124395 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI REDONDO, MARIA JOSE · 2021 to 2024
$2.6M
National institute for health and care research Exeter Biomedical Research CentreNIDDK NIH HHS K12 DK133995NIDDK NIH HHS R01 DK124395NIHR Glocal Health Award 17/63/131Randox Ltd
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
The Impact of Ancestry on Performance of Type 1 Diabetes Genetic Risk Scores: High Discrimination Performance Is Maintained in African Ancestry Populations, but Population-Specific Thresholds May Improve Risk Prediction. · full record | OpenQuestion