Evidence map›Paper›PMID 41543904›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

A bacterial translation activator with an intrinsically disordered RNA-binding region.

Pallabi Basu, Elizabeth A Farland, James C Charity, Kade A Townsend, Simon L Dove

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pallabi BasuDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-8163-7518
Elizabeth A FarlandDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.ORCID 0009-0000-7998-6404
James C CharityDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.
Kade A TownsendDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-3468-6402
Simon L DoveDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-3758-608X

Funding

Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SAHIN, MUSTAFA · 2016 to 2020
$5.2M
Characterization of a novel post-transcriptional regulator in P. aeruginosaR01AI189786 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI SIMON L DOVE, Marvin Whiteley · 2025 to 2026
$1.7M
Bacteriology PhD Training ProgramT32AI179604 · NIAID · HARVARD MEDICAL SCHOOL · PI DAVID Z RUDNER · 2025 to 2026
$655k
Identification of RNA-binding proteins in Pseudomonas aeruginosaR21AI168589 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DOVE, SIMON L · 2022 to 2023
$487k
NIAID NIH HHS R01 AI189786NIAID NIH HHS R21 AI168589NIAID NIH HHS T32 AI179604NICHD NIH HHS U54 HD090255NIH HHS AI168589NIH HHS AI179604NIH HHS AI189786
6 · The paper itself

Abstract

Bacterial RNA-binding proteins (RBPs) that control the translation of multiple transcripts act largely as negative regulators. Here, we report the identification and characterization of a positive regulator of translation (called PhaF) in the opportunistic pathogen

Indexed as

Bacterial ProteinsProtein BiosynthesisPseudomonas aeruginosaRNA-Binding ProteinsBinding SitesGene Expression Regulation, BacterialProtein BindingRNA, BacterialRNA, MessengerBacterial ProteinsRNA, BacterialRNA-Binding ProteinsRNA, MessengerIDRPhaFpost-transcriptional regulatorPseudomonas aeruginosaPslA

Identifiers

PMID41543904
PMCPMC12818456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.