Evidence map›Paper›PMID 41543884›Full record

Trial reportJMIR cancer2026

Benefits and Challenges of a Digital Exercise and Mind-Body Program During Active Cancer Treatment: Qualitative Study of Patients' Perceptions.

Karolina L Bryl, Sierra Silverwood, Krupali Desai, Kelsey Schobert, Xiaotong Li, Susan Chimonas, Jun J Mao, Erin F Gillespie

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in JMIR cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05053230 (Integrative Medicine for Patient-reported Outcomes, Values, and Experience), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05053230 naactive not recruitingnot on this map

Integrative Medicine for Patient-reported Outcomes, Values, and Experience (IMPROVE)

TypeinterventionalSponsorMemorial Sloan Kettering Cancer CenterRan2021 to 2026Enrolled324ConditionsHead and Neck Cancer, Head and Neck Tumor, Thoracic Tumor, Thoracic CancerArmsIM@Home, Enhanced usual care
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karolina L BrylIntegrative Medicine & Wellness Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.ORCID 0000-0002-1804-367X
Sierra SilverwoodDepartment of Radiation Oncology, University of Washington School of Medicine, Fred Hutch Cancer Center, Seatttle, WA, United States.ORCID 0000-0001-8505-8014
Krupali DesaiIntegrative Medicine & Wellness Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.ORCID 0000-0003-1929-6326
Kelsey SchobertIntegrative Medicine & Wellness Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.ORCID 0000-0002-5550-2505
Xiaotong LiIntegrative Medicine & Wellness Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.ORCID 0000-0003-1006-5871
Susan ChimonasDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.ORCID 0000-0002-7742-5950
Jun J MaoIntegrative Medicine & Wellness Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.ORCID 0000-0001-9229-0380
Erin F GillespieDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.ORCID 0000-0002-1386-1542

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundIndividuals undergoing cancer treatment often face a high symptom burden that impairs quality of life. Exercise and mind-body therapies have been shown to reduce symptoms but are underused. We developed a digital exercise and mind-body therapy program that effectively reduces symptoms while overcoming in-person delivery barriers. Understanding patient experiences can inform treatment mechanisms and guide digital health interventions in cancer care.

objectiveThis study aimed to explore patient experiences with Integrative Medicine at Home (IM@Home), a 12-week live digital program delivering exercise and mind-body therapies tailored to the needs of individuals undergoing cancer treatment.

methodsThis qualitative study was embedded in a randomized clinical basket trial (NCT05053230) evaluating the effects of IM@Home versus enhanced usual care on symptoms and acute health care utilization in adults with solid tumors undergoing active treatment and experiencing moderate or greater fatigue. Using maximum variation sampling, 20 participants were selected for semistructured interviews. Interviews explored participants' experiences with the program, its impact on outcomes, unmet needs, and suggestions for improvement. Transcripts were analyzed using a combined inductive and deductive thematic analysis.

resultsTwenty participants (mean age 63, SD 9.6 years; 18/20, 90% female) were interviewed. Five major themes emerged: (1) IM@Home alleviated symptom burden and supported symptom self-management; (2) IM@Home facilitated social support and information exchange; (3) IM@Home offered a flexible, tailored program in a group setting; (4) IM@Home facilitated accessible, cost-effective support; and (5) recommendations for program enhancement. IM@Home was perceived as an accessible, flexible, and supportive program that promoted physical and emotional well-being during treatment.

conclusionsIM@Home demonstrates a promising model for delivering integrative supportive care during cancer treatment. Findings highlight patient-valued features such as real-time guidance, tailored content, and community support. These insights can inform future implementation, integration into clinical care, and efforts to enhance digital mind-body interventions in oncology.

trial registrationClinicalTrials.gov NCT05053230; https://www.clinicaltrials.gov/study/NCT05053230. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1038/s41746-024-01387-z.

Indexed as

ExerciseExercise TherapyMind-Body TherapiesNeoplasmsQuality of LifeAgedFemaleHumansMaleMiddle AgedQualitative ResearchTelemedicinedigital healthexerciseintegrative medicineintegrative oncologymind-body therapiesqualitative researchsupportive cancer caresymptom managementtelehealth

Identifiers

PMID41543884
PMCPMC12859541

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.