ArticleJournal of epidemiology and global health2026
Adaptation and Psychometric Validation of the Arabic EuroQol-5D-5L among Sepsis Survivors in Saudi Arabia.
Article in Journal of epidemiology and global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSepsis significantly impairs long-term health-related quality of life (HRQoL). The EuroQol-5D-5 L (EQ-5D-5L) is a validated tool for measuring HRQoL in acute illness; however, there is no validated Arabic version for sepsis survivors. This study aimed to validate an Arabic version of the EQ-5D-5L in sepsis survivors.
methodsWe conducted a cross-sectional validation study between 2024 and 2025 at Prince Sultan Military Medical City in Riyadh, Saudi Arabia. We recruited sepsis survivors aged ≥ 18 years who agreed to participate in this study. Four bilingual translators performed forward and backward translation of the EQ-5D-5L. Research coordinators conducted phone interviews with participants or their caregivers and administered the Arabic EQ-5D-5L instrument twice, at baseline and at two weeks, and a validated Arabic version of the SF-36 Health Survey. All patients completed the test-retest assessment. We assessed convergent validity by measuring the correlation between conceptually related domains of EQ-5D-5L and SF-36 questionnaires. We measured intraclass correlation coefficients (ICC) to assess test-retest reliability.
resultsFifty-five sepsis survivors were recruited using a consecutive sampling method and consented to participate in the study. Participants had a median age of 62 years (interquartile range: 36–71), and 45.5% were male. Overall, 45 (81.8%) participants had sepsis, while 10 (18.2%) had septic shock. The median EQ-5D index score was 0.63 (IQR: 0.14–0.96), and the median visual analogue scale score for quality of life was 60 (IQR: 50–80). The Arabic EQ-5D-5L demonstrated a strong correlation between the EQ-5D-5L index and SF-36 Physical Component Summary (Spearman’s Rho = 0.83, P < 0.001) and Mental Component Summary (Rho = 0.84, P < 0.001). Convergent validity was confirmed through strong correlations between conceptually related domains. Test-retest reliability showed an ICC ranging from 0.52 to 0.90 across domains.
conclusionsThe Arabic EQ-5D-5L shows strong psychometric properties and is a valid tool for assessing HRQoL among Arabic-speaking sepsis survivors. It can support clinical assessment, outcome tracking, and rehabilitation planning in this population.
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