Observational studyEuropean geriatric medicine2026
Hemoglobin and transferrin saturation are associated with mobility and physical function two months after hip fracture surgery: an observational cohort study.
Observational study in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Article
- Assessment of physical function of hospitalized older patients in routine clinical practice predicts 1-year mortality; A cohort study of 5,062 medical and surgical patients.European geriatric medicine · 2026Article
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14 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate whether hemoglobin two days after discharge and transferrin saturation two months after discharge for hip fracture (HF) were associated with mobility and functional outcomes.
methodsWe included patients ≥ 65 years, surgically treated for a hip fracture at Copenhagen University Hospital, Bispebjerg and Frederiksberg. Iron deficiency was defined as transferrin saturation (TSAT) below 20%. Mobility and physical function were measured two months after discharge in an orthogeriatric outpatient clinic using new mobility score (0-9 points, 9 best functional mobility), six-minute walk test, usual walking speed (10-m), 30-s Sit-to-Stand test, and handgrip strength. Associations between hemoglobin, transferrin saturation (per units of 10%) and outcomes were evaluated by multivariable linear regression, with age, sex, and type of fracture (intra- versus extracapsular) as covariates.
results235 patients were included (69% women, age 80 ± 8 years, 55% had intra-capsular fractures). The average ± SD hemoglobin two days after discharge was 10.4 ± 1.5 g/dL, 91% had anemia according to the WHO definition. The average transferrin saturation two months after surgery was 0.21 ± 0.09, 51% had iron deficiency. High hemoglobin was associated with high new mobility score (B = 0.46, 95% CI 0.25-0.66, p < 0.001). High transferrin saturation was associated with high new mobility score (B = 0.74, 95% CI 0.17-1.31, p = 0.01), six-minute walk test (B = 47, 95% CI 16-78, p = 0.004), walking speed (B = 0.12, 95% CI 0.06-0.19, p < 0.001), 30-s Sit-to-Stand test (B = 1.56, 95% CI 0.30-2.85, p = 0.01), and hand grip strength (B = 2.1, 95% CI 0.0-4.2, p = 0.049).
conclusionsHigh hemoglobin two days after discharge was associated with high new mobility score two months after surgery. Transferrin saturation was associated with mobility and all measured functional outcomes two months after hip fractures.
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