Evidence map›Paper›PMID 41543748›Full record

ArticleEuropean journal of nutrition2026

Development and evaluation of a nutrient-derived anti-inflammatory dietary index (NADI) among Chinese adults.

Yuxiang Yang, Shuya Cai, Tamas Szili-Torok, Wei Piao, Kun Huang, Changyuan Yang, Huifang Xue, Jing Nan, Fusheng Li, Dongmei Yu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuxiang YangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.ORCID http://orcid.org/0000-0001-5491-4789
Shuya CaiNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Tamas Szili-TorokDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-8675-9234
Wei PiaoNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Kun HuangDepartment of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Changyuan YangDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Huifang XueDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Jing NanNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Fusheng LiNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Dongmei Yu *National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, China. yudm@ninh.chinacdc.cn.ORCID http://orcid.org/0009-0005-6677-6279
Changzheng Yuan *School of Public Health, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China. chy478@zju.edu.ORCID http://orcid.org/0000-0002-2389-8752
Martin H de BorstDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-4127-8733

Funding

China Scholarship Council 202408110159Danone Dietary Nutrition Research and Education Fund: The relationship between dietary inflammation index and chronic diseases among Chinese adults DIC2023-03Public Health Emergency Project Nutrition Health and Healthy Diet Campaign 102393220020070000012
6 · The paper itself

Abstract

purposeTo develop and evaluate an anti-inflammatory dietary index based on the specific dietary culture and preference among Chinese adults.

methodsA total of 6322 participants were included and were further separated into a training (n = 4514) and a validation set (n = 1808). In the training set, we utilized reduced rank regression to derive a dietary index based on the intake of 33 food groups and five pre-identified anti-inflammatory nutrients. In the validation set, interleukin (IL)-1β, IL-4, IL-6, and high-sensitivity C-reactive protein (hs-CRP) were measured, and a total inflammation score (TIS) was constructed. Pearson partial correlation analysis and multivariate generalized linear regression were applied to explore the relationship between dietary indices and inflammatory biomarkers.

resultsThe derived dietary index, termed Nutrient-derived Anti-inflammatory Dietary Index (NADI), mainly characterized by a higher intake of fresh vegetables and fruits, mushrooms and fungi, soybeans, fresh eggs, and tea, alongside a lower intake of red meat, alcohol, and refined grains. NADI significantly correlated with several well-established dietary indices. Participants in the highest quintile of NADI had lower plasma levels of IL-1β (relative concentration [RC]: 0.67, 95% CI 0.58 ~ 0.77), hs-CRP (RC: 0.68, 95% CI 0.58 ~ 0.80), and TIS (RC: 0.43, 95% CI 0.31 ~ 0.59) compared with the lowest quintile in the fully adjusted model. Results were similar in subgroups and sensitivity analyses.

conclusionsNADI effectively captures inflammation-related dietary quality and could serve as a valuable instrument for evaluating the impact of dietary inflammatory potential on health outcomes in Chinese adults.

Indexed as

Anti-Inflammatory AgentsDietInflammationNutrientsAdultBiomarkersChinaC-Reactive ProteinDiet SurveysFemaleHumansInterleukin-1betaMaleMiddle AgedAnti-Inflammatory AgentsBiomarkersC-Reactive ProteinInterleukin-1betaNutrientsDietary indexDietary inflammatory potentialInflammationReduced rank regression

Identifiers

PMID41543748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.