Evidence map›Paper›PMID 41543510›Full record

ArticleMicrobiology spectrum2026

Bidirectional relationship between the biofilm of

David Dumoulin, Mnar Ghrayeb, Sarah Côté, Daniel Garneau, Liraz Chai, Eric H Frost, Tamàs Fülöp, Pascale B Beauregard

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Microbiota-Gut-Brain Axis in Neurodegenerative Diseases: The Role of Bacterial Amyloids.Cellular and molecular gastroenterology and hepatology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David DumoulinDépartement de Biologie, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Mnar GhrayebInstitute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.
Sarah CôtéDépartement de Biologie, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Daniel GarneauDépartement de Biologie, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Liraz ChaiInstitute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.
Eric H FrostDépartement de Microbiologie et Infectiologie, Faculté de Médecine et de Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Tamàs FülöpCentre de Recherche sur le vieillissement, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Pascale B BeauregardDépartement de Biologie, Université de Sherbrooke, Sherbrooke, Quebec, Canada.ORCID 0000-0003-2947-0500

Funding

Fonds de recherche du Québec 2019-AUDC-263669Fonds de Recherche du Québec - Santé 316403Ministère des relations internationales et de la Francophonie
6 · The paper itself

Abstract

Periodontitis and IMPORTANCE: While the etiology of Alzheimer's disease has been studied extensively for the past 50 years, its exact causes remain unknown. Our current understanding is that the accumulation of multiple genetic and environmental risk factors would lead to the onset of the disease.

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesBacteroidaceae InfectionsPorphyromonas gingivalisBiofilmsExtracellular MatrixHumansPeptide FragmentsPeriodontitisAmyloid beta-Peptidesamyloid beta-protein (1-40)amyloid beta-protein (1-42)Peptide FragmentsAlzheimer’s diseasebiofilmperiodontitisPorphyromonas gingivalis

Identifiers

PMID41543510
PMCPMC12955484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.