Trial reportAnnals of cardiac anaesthesia2026
Efficacy of Ropivacaine Infiltration by Presternal Multi-orifice Catheter for Post-Sternotomy Pain Relief in Adult Patients Undergoing Cardiac Surgery-A Prospective, Randomized, Control Study.
Trial report in Annals of cardiac anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsPost-sternotomy pain management remains a key concern in adult cardiac surgery. This study evaluated the efficacy and safety of ropivacaine infiltration via a presternal multi-orifice catheter for postoperative analgesia.
designA prospective randomized controlled trial.
settingA single tertiary care center. MATERIAL AND
methodsA total of 175 adult patients undergoing cardiac surgery via median sternotomy were randomized into three groups: Group A (n = 58): Received 0.375% ropivacaine as continuous infusion at 5 mL/hour, Group B (n = 58): Received 5 mL of 0.375% ropivacaine as intermittent boluses every 8 hours, and Group C (n = 59): Received conventional intravenous tramadol. Pain was assessed using the visual analogue scale (VAS) for 48 hours post-extubation. Intravenous tramadol was used as rescue analgesia if VAS≥3.
resultsGroup B reported significantly lower VAS scores and rescue tramadol requirements (56 ± 35 mg) compared to Group A (155 ± 32 mg) and Group C (135 ± 45 mg). No significant differences were observed among the groups regarding hemodynamic parameters, catheter-related infections, time to extubation, or intensive care unit (ICU) stay.
conclusionPresternal infiltration of 0.375% ropivacaine is safe and effective for post-sternotomy analgesia. The intermittent bolus technique provides superior pain relief and reduces opioid consumption compared to continuous infusion and standard intravenous analgesia.
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