Evidence map›Paper›PMID 41543401›Full record

ArticleAnnals of cardiac anaesthesia2026

Role of Non-catecholamines Vasopressors in the Management of Vasoplegic Syndrome after Cardiopulmonary Bypass: A Scoping Review.

Amarjeet Kumar, Athira Jayan, Poonam Kumari, Kunal Singh, Aakanksha Hiremath

Abstract readScoping Review
In one paragraph

Article in Annals of cardiac anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amarjeet KumarDepartment of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Athira JayanDepartment of Anaesthesiology, All India Institute of Medical Sciences, New Delhi, India.
Poonam KumariDepartment of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Kunal SinghDepartment of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Aakanksha HiremathDepartment of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasoplegic syndrome is a life-threatening condition characterized by uncontrolled peripheral vasodilation, leading to profound arterial hypotension. Treatments include catecholamines, vasopressin, methylene blue (MB), hydroxocobalamin, angiotensin II, and ascorbic acid. We developed a scoping review protocol according to the Joanna Briggs Institute methodology and searched PubMed, PubMed Central, Scopus, and Cochrane Library electronic databases. A total of 23 records were included in this scoping review, out of which 13 were original research studies, seven were reviews, and three were case studies. In these studies, vasopressin, MB, hydroxocobalamin, angiotensin II, and ascorbic acid were used for vasoplegic syndrome. Vasopressin, MB, hydroxocobalamin, angiotensin II, and ascorbic acid showed rapid restoration of hemodynamics and decreased vasopressor requirement. Non-catecholamine drugs such as vasopressin, angiotensin II, MB, and hydroxocobalamin appear to be promising drugs for the treatment of patients with post-cardiac surgery vasoplegic syndrome. It is demonstrated to be effective in raising blood pressure in such patients, but these agents should be used cautiously due to their associated adverse effects.

Indexed as

Cardiopulmonary BypassPostoperative ComplicationsVasoconstrictor AgentsVasoplegiaAngiotensin IIAscorbic AcidHumansHydroxocobalaminMethylene BlueVasopressinsAngiotensin IIAscorbic AcidHydroxocobalaminMethylene BlueVasoconstrictor AgentsVasopressinsCardiac surgerycardiopulmonary bypassvasoplegiavasopressor

Identifiers

PMID41543401
PMCPMC12935108

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.