Evidence map›Paper›PMID 41543356›Full record

ArticleNanoscale horizons2026

Simultaneous detection of lymphocytes and tumor cells

Siddhant Kothadiya, Gabriel P Cutshaw, Ansuja P Mathew, Casey Zielinski, Rizia Bardhan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale horizons, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siddhant KothadiyaDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA. rbardhan@iastate.edu.ORCID http://orcid.org/0009-0009-5782-6448
Gabriel P CutshawDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA. rbardhan@iastate.edu.ORCID http://orcid.org/0000-0003-0474-0631
Ansuja P MathewDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA. rbardhan@iastate.edu.
Casey ZielinskiDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA. rbardhan@iastate.edu.
Rizia BardhanDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA. rbardhan@iastate.edu.ORCID http://orcid.org/0000-0002-5854-652X

Funding

Developing Multimodal Multiplexed ImmunoPET-Raman Probes to Guide ImmunotherapiesR01EB029756 · NIBIB · IOWA STATE UNIVERSITY · PI BARDHAN, RIZIA · 2020 to 2024
$1.2M
NIBIB NIH HHS R01 EB029756
6 · The paper itself

Abstract

Immunotherapies show heterogeneous response in patients and identifying those likely to benefit from these therapies remains challenging. This is in part because histopathology, the current clinical standard, cannot accurately predict response. Dynamic changes occur in both tumor cells and immune cells

Indexed as

CD8-Positive T-LymphocytesGoldImmunotherapyMembrane ProteinsMetal NanoparticlesToll-Like Receptor 9AnimalsCell Line, TumorFemaleMiceMice, Inbred BALB CSpectrum Analysis, RamanSTING ProteinVascular Endothelial Growth Factor Receptor-2GoldMembrane ProteinsSting1 protein, mouseSTING ProteinTlr9 protein, mouseToll-Like Receptor 9Vascular Endothelial Growth Factor Receptor-2

Identifiers

PMID41543356
PMCPMC12810492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.