Evidence map›Paper›PMID 41543284›Full record

ArticleEuropean journal of immunology2026

Shared HLA-E and Mamu-E Peptide Repertoires With Subtle Peptide Binding Differences Revealed by Combined nDSF- and Fluorescence Polarisation-Based Methods.

Max N Quastel, Sashini A Ranawana, Bas W A Peeters, Andy van Hateren, Andrew J McMichael, Geraldine M Gillespie

Abstract read
In one paragraph

Article in European journal of immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Max N QuastelNuffield Department of Medicine, Centre for Immuno-Oncology, University of Oxford, Oxford, UK.
Sashini A RanawanaNuffield Department of Medicine, Centre for Immuno-Oncology, University of Oxford, Oxford, UK.
Bas W A PeetersNuffield Department of Medicine, Centre for Immuno-Oncology, University of Oxford, Oxford, UK.
Andy van HaterenInstitute For Life Sciences and Centre for Cancer Immunology, Faculty of Medicine, University of Southampton, Southampton, UK.
Andrew J McMichaelNuffield Department of Medicine, Centre for Immuno-Oncology, University of Oxford, Oxford, UK.
Geraldine M GillespieNuffield Department of Medicine, Centre for Immuno-Oncology, University of Oxford, Oxford, UK.ORCID 0000-0002-1075-870X

Funding

Collaboratory of AIDS Researchers for Eradication (CARE)UM1AI164567 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2021 to 2026
$31.6M
Non-canonical epitope presentation and antigen processing by MHC-ER01AI175459 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Klaus J Fruh, Jonah B. Sacha · 2023 to 2026
$2.8M
NIAID NIH HHS R01 AI175459NIAID NIH HHS UM1 AI164567NIH HHS R01 AI 175459NIH HHS UM1 AI 164567-02The Gates Foundation INV-055780The Wellcome Trust 227388/Z/23/ZWellcome Trust
6 · The paper itself

Abstract

The primary function of MHC-E-human leukocyte antigen (HLA)-E in humans and Mamu-E in rhesus macaques-relates to immune surveillance via CD94/NKG2x receptors expressed on NK cells. However, a secondary role where MHC-E presents immunogenic peptides to CD8

Indexed as

Fluorescence PolarizationHistocompatibility Antigens Class IPeptidesAnimalsCD8-Positive T-LymphocytesHLA-E AntigensHumansMacaca mulattaProtein BindingHistocompatibility Antigens Class IHLA-E AntigensPeptidesfluorescence polarisationHLA‐EMamu‐EMHC‐Enano‐differential scanning fluorimetrypeptide binding

Identifiers

PMID41543284
PMCPMC12810216

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.