ReviewJournal of medical virology2026
Cross-Species Insights Into Gamma Herpesvirus Transcriptomes: Long-Read and Multi-Omics Perspectives.
Review in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Cross-Species Insights Into Gamma Herpesvirus Transcriptomes: Long-Read and Multi-Omics Perspectives.Journal of medical virology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Comparative transcriptome analyses of gamma herpesviruses have been revolutionized by long-read sequencing and integrative multi-omics approaches, enabling unprecedented resolution of viral gene expression. Cross-species studies of Kaposi's sarcoma-associated herpesvirus (KSHV), Epstein-Barr virus (EBV), and murine gamma herpesvirus 68 (MHV68) have uncovered a vast diversity of transcript isoforms, including alternative 5'/3' UTR variants, alternative splice isoforms, and transcripts encoding truncated or extended coding sequences. These efforts revealed novel transcript isoforms harboring partial open reading frames, entirely new ORFs, and an expanding repertoire of viral non-coding RNAs. Additional regulatory mechanisms, such as promoter dependence on viral replication factors, selective polyadenylation site usage, frameshifting via alternative splicing, and extensive readthrough transcription, further illustrate the complex strategies governing gamma herpesvirus transcriptomes. This review synthesizes these discoveries, highlighting transcriptional strategies employed by gamma herpesviruses for persistence through different phases of replication, while outlining how integrative transcriptomics has reshaped our understanding of herpesvirus gene regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.