Evidence map›Paper›PMID 41542786›Full record

SynthesisGerodontology2026

The Impact of Periodontitis on Oral Health Outcomes in Older Adults: A Systematic Review.

Lewis Winning, Kristina Bertl, Ioannis Polyzois, Yvonne Van der Waal, Rawan Kahatab, Peter Harrison, Gerry McKenna

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in Gerodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lewis WinningDublin Dental University Hospital, Trinity College, Dublin, Ireland.ORCID https://orcid.org/0000-0002-8783-8089
Kristina BertlDepartment of Periodontology, Dental Clinic, Faculty of Medicine, Sigmund Freud University, Vienna, Austria.ORCID https://orcid.org/0000-0002-8279-7943
Ioannis PolyzoisDublin Dental University Hospital, Trinity College, Dublin, Ireland.ORCID https://orcid.org/0000-0002-0921-0843
Yvonne Van der WaalUniversity of Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-5638-462X
Rawan KahatabDublin Dental University Hospital, Trinity College, Dublin, Ireland.ORCID https://orcid.org/0009-0002-0493-8015
Peter HarrisonDublin Dental University Hospital, Trinity College, Dublin, Ireland.ORCID https://orcid.org/0000-0001-7526-4834
Gerry McKennaCentre of Public Health, Queen's University of Belfast Institute of Clinical Sciences, Belfast, UK.ORCID https://orcid.org/0000-0001-8478-1673

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo systematically review the impact of periodontitis on clinical oral health outcomes and oral health-related quality of life (OHRQoL) in older adults (≥ 60 years).

backgroundGlobal evidence shows that severe periodontitis prevalence peaks in the 60s, yet how periodontitis relates specifically to oral health outcomes in older adults has not been comprehensively synthesised. Prior reviews in mixed-age populations demonstrate strong links with tooth loss but less consistent associations with OHRQoL.

methodsThis systematic review followed PRISMA guidelines and was registered on PROSPERO (CRD420251010568). Searches of PubMed, MEDLINE, Embase, Scopus, and Cochrane Library (to May 2025) identified studies of adults ≥ 60 years with periodontitis reporting oral health outcomes or OHRQoL. Two reviewers independently screened studies, extracted data, and assessed risk of bias.

resultsForty-three studies met inclusion criteria: 18 longitudinal studies on clinical outcomes and 25 cross-sectional studies on OHRQoL. Clinical studies consistently demonstrated that deeper baseline periodontal pockets, greater clinical attachment loss, and higher CPI/CPITN scores predicted adverse outcomes over 18 months to 12 years follow-up, including tooth loss, further attachment loss, and functional decline. OHRQoL studies showed inconsistent findings, with roughly equal numbers reporting significant associations versus no relationship.

conclusionsIn adults ≥ 60 years, periodontitis consistently predicts tooth loss and continued periodontal breakdown, whereas OHRQoL associations are inconsistent and appear mediated primarily through downstream consequences such as tooth loss and functional impairment, though direct effects may occur in advanced disease. These findings emphasise the importance of periodontal prevention and management in older adults.

Indexed as

Oral HealthPeriodontitisQuality of LifeAgedHumansMiddle AgedTooth LossgerodontologyOHRQoLperiodontitissystematic reviewtooth loss

Identifiers

PMID41542786
PMCPMC13498920

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.