Evidence map›Paper›PMID 41542706›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Eating Disorders and Parkinson's Disease - 1: Comorbidities, Neurobiology and Family History.

Angeline Krueger, Andrew W Bergen, Irene Litvan, Vincent Filoteo, Carolina Makowski, Susan Murray, Karlee McGlone, Michael Garvin, Andi Drouin, Alyssa Kauffman and 2 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Angeline KruegerUniversity of California San Diego, La Jolla, CA, USA.
Andrew W BergenOregon Research Institute, Springfield, OR, USA.ORCID 0000-0002-1237-7644
Irene LitvanUniversity of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-3485-3445
Vincent FiloteoUniversity of California San Diego, La Jolla, CA, USA.
Carolina MakowskiUniversity of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-8816-4549
Susan MurrayUniversity of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-3246-0357
Karlee McGloneUniversity of California San Diego, La Jolla, CA, USA.
Michael GarvinWilliwaw Biosciences, LLC, Clarkston, MI, USA.ORCID 0000-0002-2204-7569
Andi DrouinUniversity of California San Diego, La Jolla, CA, USA.
Alyssa KauffmanUniversity of California San Diego, La Jolla, CA, USA.
Caroline SteeleUniversity of California San Diego, La Jolla, CA, USA.
Walter H KayeUniversity of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-4478-4906

Funding

Technology and Remote Assessment CoreU19AG063911 · NIA · MAYO CLINIC ROCHESTER · PI ADAM L. BOXER, Bradley F Boeve · 2019 to 2026
$120.9M
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOUGLAS R GALASKO · 2019 to 2026
$34.9M
The Progressive Supranuclear Palsy Clinical Trial Platform (PTP)R01AG085029 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BOXER, ADAM L., LITVAN, IRENE · 2024 to 2025
$30.3M
Dementia with Lewy Bodies Consortium - Supplement for ASL sequenceU01NS100610 · NINDS · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI DOUGLAS R GALASKO, JAMES Bruce LEVERENZ · 2016 to 2026
$15.6M
Assessing skin biomarkers for preclinical diagnosis of PD and non-PD ParkinsonismU01NS112010 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI CHEN, SHU G., GUNZLER, STEVEN A. · 2019 to 2023
$3.7M
NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG085029NIA NIH HHS U19 AG063911NINDS NIH HHS U01 NS100610NINDS NIH HHS U01 NS112010
6 · The paper itself

Abstract

Objective: In response to a clinical observation of an Anorexia Nervosa (AN) patient with family history of Parkinson's Disease (FHoPD), and evidence of similarities in dopamine function, personality, anxiety and weight loss symptoms between AN and PD, we completed a pilot study to estimate FHoPD in families of those with eating disorders (EDs). Method: We ascertained FHoPD among ED patients and community participants, and estimated relative risks (RRs) for AN, Bulimia Nervosa (BN) and Binge Eating Disorder (BED). Results: We observed increased FHoPD among patients and community participants (N=482) meeting criteria for ED diagnoses compared to community participants (N=394) without an ED diagnosis. For AN, FHoPD prevalence was 6.6% vs 3.4%, χ Conclusions: EDs are associated with an elevated FHoPD. Translational analyses leveraging disorder-specific research resources may benefit our understanding of the genetics and neuroscience of both disorders.

Indexed as

Anorexia NervosaAnxietyBulimia NervosaDopaminergic NeuronsFeeding and Eating DisordersMedical History TakingParkinson’s DiseaseTemperament

Identifiers

PMID41542706
PMCPMC12803308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.