Evidence map›Paper›PMID 41542666›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Molecular, Transcriptomic, and Proteomic Characterization of

Maria Nikulkova, Anne Kessler, Ziyi Wang, Abhishek Patel, Tirusew Tolessa, Taye Teka, Daniel Tesfaye, Biniam Lukas, Deje Lemessa, Marta Zemede and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Maria NikulkovaJohns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Anne KesslerJohns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Ziyi WangJohns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Abhishek PatelCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, NY, United States.
Tirusew TolessaTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Taye TekaTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Daniel TesfayeTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Biniam LukasTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Deje LemessaTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Marta ZemedeTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Fikirte LegesseTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Harsh SrivastavaJohns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Steven A SullivanJohns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Guiyun YanProgram in Public Health, University of California, Irvine, United States.
Delenasaw YewhalawTropical and Infectious Diseases Research Centre, Jimma University, Jimma, Ethiopia.
Jane M CarltonJohns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.ORCID 0000-0001-9340-5020

Funding

Using Next-Generation Genomics to Study Antimalarial Drug Resistance in IndiaU19AI089676 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARLTON, JANE M · 2010 to 2023
$22.6M
NIAID NIH HHS U19 AI089676
6 · The paper itself

Abstract

Background: Failure of rapid diagnostic tests (RDTs) to detect Methods: We consented and enrolled 148 individuals with suspected malaria presenting to health clinics in Mizan Aman, Ethiopia. We administered a clinical questionnaire, diagnosed the presence of malaria parasites via RDT, and collected venous blood. Samples were assayed using molecular methods to detect parasite DNA, Results: We identified 29/148 (27.9%) individuals as Conclusions: Our molecular, transcriptomic, and proteomic characterization of

Indexed as

diagnostic escapeEthiopiaMalariaPlasmodiumproteomicsrapid diagnostic test

Identifiers

PMID41542666
PMCPMC12803298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.