ArticlebioRxiv : the preprint server for biology2026
Dynamic control of Raf-ERK signaling modulates neuronal activity across biological scales.
Huaxun Fan, Eunjoo Kang, Yuan Zhou, Collin Barnes, Nathan Gron, Hairuo Du, Catherine A Christian-Hinman, Xinzhu Yu, Kai Zhang
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Huaxun FanDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.ORCID 0000-0003-3657-9758 Eunjoo KangNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Yuan ZhouDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Collin BarnesDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Nathan GronDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Hairuo DuNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Catherine A Christian-HinmanNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Xinzhu YuNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Kai ZhangDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.ORCID 0000-0002-6687-4558 Funding
Functional, Structural and Molecular Decoding of Astrocyte-Neuron InteractionDP2NS136871 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Xinzhu Yu · 2023 to 2026
$2.4MMechanism of Gp1 mGluR-dependent translation and plasticityR01MH124827 · NIMH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI TSAI, NIEN-PEI, ZHANG, KAI · 2021 to 2025
$2.3MNeural and pituitary mechanisms linking epilepsy to co-morbid reproductive endocrine dysfunctionR01NS105825 · NINDS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHRISTIAN-HINMAN, CATHERINE A · 2018 to 2022
$1.8MAstrocytic regulation of prefrontal neural circuits and avoidance behaviorR01MH132556 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Xinzhu Yu · 2024 to 2026
$1.7MPrecise regulation of native transcription factor at the single-cell levelR01GM132438 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ZHANG, KAI · 2019 to 2022
$1.4MNIGMS NIH HHS R01 GM132438NIMH NIH HHS R01 MH124827NIMH NIH HHS R01 MH132556NINDS NIH HHS DP2 NS136871NINDS NIH HHS R01 NS105825
6 · The paper itselfAbstract
Neuronal activity robustly engages the extracellular signal-regulated kinase (ERK) signaling pathway through Ca
Identifiers
PMID41542629
PMCPMC12803210
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390