Evidence map›Paper›PMID 41542601›Full record

ArticlebioRxiv : the preprint server for biology2026

Mechanistic insights into

Ahmed Hassan, Yuko Nakano, Howard Gamper, Isao Masuda, Matyas Pinkas, Sathya Nagarajan, Jonathan Dworkin, Gregor Blaha, Ya-Ming Hou, Gabriel Demo

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Ahmed HassanCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.
Yuko NakanoDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, USA.
Howard GamperDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, USA.
Isao MasudaDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, USA.
Matyas PinkasCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.
Sathya NagarajanDepartment of Microbiology and Immunology, Columbia University, New York, USA.
Jonathan DworkinDepartment of Microbiology and Immunology, Columbia University, New York, USA.
Gregor BlahaDepartment of Biochemistry, University of California, Riverside, California, USA.
Ya-Ming HouDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, USA.
Gabriel DemoCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.

Funding

tRNA in codon usageR35GM134931 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2020 to 2025
$5.4M
Discovery of Gram-negative permeable chemical probes for tRNA methylationR01AI139202 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2019 to 2022
$2.4M
The tRNA pool in C9-ALS/FTDR21AG082005 · NIA · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2023 to 2024
$445k
NIAID NIH HHS R01 AI139202NIA NIH HHS R21 AG082005NIGMS NIH HHS R35 GM134931
6 · The paper itself

Abstract

Bacteria survive hostile conditions in clinically relevant conditions by shutting down protein synthesis, but how they restart growth remains poorly understood. Here, we use an

Indexed as

initiation factor IF1initiation factor IF3Ribosome assemblyRimMRsfS anti-association

Identifiers

PMID41542601
PMCPMC12803275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.